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高橋 宏

職名講師
専攻・専門分野医療統計学
主な担当科目理学療法研究概論


メッセージ

「世の中には三つのウソがある。一つはウソ、一つは真っ赤なウソ、そして統計」
19世紀英国の宰相B・ディズレイリの言葉です。誤った統計による数値で政策判断を行うことの危険性を彼はよく知っていました。
一方、ほぼ同時代のご存じF・ナイチンゲールが英国王立統計学会の会員であったことはあまり知られていません。曰く「神のみ心を知るために我々は統計学を学ばなくてはならない」。ダーウィンの進化論が登場したばかりの時代ですから、この「神のみ心」とは自然の真理という意味と思われます。
統計学は科学的な立証に不可欠だが、同時に誤った推論を導くこともあり得る。ここが肝要です。

略歴

1981年4月名古屋工業大学機械工学科卒
1981年4月名古屋共立病院臨床工学科入職
2003年4月同学術局長
2012年5月藤田保健衛生大学学術研究支援課長
2012年5月同医学部腎臓内科特別研究員
2014年4月同医療科学部兼任講師
2017年3月同医療科学部リハビリテーション学科講師

研究・業績

論文

  1. Ishii H, Takahashi H, Ito Y, Aoyama T, Kamoi D, Sakakibara T, Umemoto N, Kumada Y, Suzuki S, Murohara T. The Association of Ankle Brachial Index, Protein-Energy Wasting, and Inflammation Status with Cardiovascular Mortality in Patients on Chronic Hemodialysis. Nutrients. 2017; 9 (4), 416.
  2. Takahashi H, Inoue K, Shimizu K, Hiraga K, Takahashi E, Otaki K, Yoshikawa T, Furuta K, Tokunaga C, Sakakibara T, Ito Y; Tokai Renal Nutrition Study Group. Comparison of Nutritional Risk Scores for Predicting Mortality in Japanese Chronic Hemodialysis Patients. J Ren Nutr. 2017; 27 (3): 201-206.
  3. Okuyama R, Ishii J, Takahashi H, Kawai H, Muramatsu T, Harada M, Yamada A, Motoyama S, Matsui S, Naruse H, Sarai M, Hasegawa M, Watanabe E, Suzuki A, Hayashi M, Izawa H, Yuzawa Y, Ozaki Y. Combination of high-sensitivity troponin I and N-terminal pro-B-type natriuretic peptide predicts future hospital admission for heart failure in high-risk hypertensive patients with preserved left ventricular ejection fraction. Heart Vessels. 2017 (in press).
  4. Yajima T, Yajima K, Hayashi M, Takahashi H, Yasuda K. Efficacy and safety of teneligliptin in addition to insulin therapy in type 2 diabetes mellitus patients on hemodialysis evaluated by continuous glucose monitoring. Diabetes Res Clin Pract. 2016; 122: 78-83.
  5. Kitagawa F, Ishii J, Hiramitsu S, Takahashi H, Okuyama R, Kawai H, Muramatsu T, Harada M, Motoyama S, Naruse H, Matsui S, Sarai M, Hayashi M, Watanabe E, Izawa H, Ozaki Y. Assessment of trough rivaroxaban concentrations on markers of coagulation activation in nonvalvular atrial fibrillation population. Heart Vessels. 2017; 32 (5): 609-617.
  6. Sato H, Maeda K, Morise Z, Takahashi H, Sugihara K; Japanese Study Group for Postoperative Follow-up of Colorectal Cancer. Clinical outcomes of stage IV colorectal cancer after R0 resection: a multi-institutional retrospective analysis. Int J Clin Oncol. 2017; 22 (2): 297-306.
  7. Hayano J, Yasuma F, Watanabe E, Carney RM, Stein PK, Blumenthal JA, Arsenos P, Gatzoulis KA, Takahashi H, Ishii H, Kiyono K, Yamamoto Y, Yoshida Y, Yuda E, Kodama I. Blunted cyclic variation of heart rate predicts mortality risk in post-myocardial infarction, end-stage renal disease, and chronic heart failure patients. Europace. 2016 ( in press).
  8. Kondo A, Takahashi K, Mizuno T, Kato A, Hirano D, Yamamoto N, Hayashi H, Koide S, Takahashi H, Hasegawa M, Hiki Y, Yoshida S, Miura K, Yuzawa Y. The Level of IgA Antibodies to Endothelial Cells Correlates with Histological Evidence of Disease Activity in Patients with Lupus Nephritis. PLoS One. 2016; 11 (10).
  9. Kumada Y, Ishii H, Aoyama T, Kamoi D, Kawamura Y, Sakakibara T, Nogaki H, Takahashi H, Murohara T. Bypass Surgery Versus Endovascular Therapy in Chronic Hemodialysis Patients with Critical Limb Ischemia due to Infra-inguinal Disease. J Am Coll Cardiol 2016 ( in press).
  10. Torii Y, Fujii T, Kukimoto I, Saito M, Iwata T, Takahashi H, Ichikawa R, Kawai S, Otani S, Aok D. Comparison of methods using paraffin-embedded tissues and exfoliated cervical cells to evaluate HPV genotype attribution. Cancer research 2016 (in press).
  11. Sato H, Kotake K, Sugihara K, Takahashi H, Maeda K, Uyama. Clinicopathological Factors Associated with Recurrence and Prognosis after R0 Resection for Stage IV Colorectal Cancer with Peritoneal Metastasis. Dig Surg 2016; 33(5): 382-91.
  12. Hasegawa M, Ishii J, Kitagawa F, Takahashi H, Sugiyama K, Tada M, Kanayama K, Takahashi K, Hayashi H, Koide S, Nakai S, Ozaki Y, Yuzawa Y. Plasma Neutrophil Gelatinase-Associated Lipocalin as a Predictor of Cardiovascular Events in Patients with Chronic Kidney Disease. Biomed Res Int 2016 (in press).
  13. Yajima T, Yajima K, Hayashi M, Yasuda K, Takahashi H, Yamakita N. Serum albumin-adjusted glycated albumin is a better predictor of mortality in diabetic patients with end-stage renal disease on hemodialysis. J Diabetes Complications. 2016 (in press).
  14. Nagahara Y, Motoyama S, Sarai M, Ito H, Kawai H, Takakuwa Y, Miyagi M, Shibata D, Takahashi H, Naruse H, Ishii J, Ozaki Y. Eicosapentaenoic acid to arachidonic acid (EPA/AA) ratio as an associated factor of high risk plaque on coronary computed tomography in patients without coronary artery disease. Atherosclerosis 2016; 250: 30-37.
  15. Umemoto N, Ishii H, Kamoi D, Aoyama T, Sakakibara T, Takahashi H, Tanaka A, Yasuda Y, Suzuki S, Matsubara T, Murohara T. Reverse association of omega-3/omega-6 polyunsaturated fatty acids ratios with carotid atherosclerosis in patients on hemodialysis. Atherosclerosis 2016; 249: 65-69.
  16. Ozeki S, Maeda K, Hanai T, Masumori K, Katsuno H, Takahashi H, Effects of robotic rectal surgery on sexual and urinary functions in male patients. Surg Today 2016; 46 (4): 491-500.
  17. Tosaka N, Akamatsu H, Fujii N, Takahashi H, Yoshida S. A new method of quantitatively analyzing thoracic CT images to diagnose connective tissue disease-associated interstitial pneumonia. Clin Rheumatol 2015; 34(12): 2113-8.
  18. Kusaka M, Kubota Y, Sasaki H, Fukami N, Fujita T, Hirose Y, Takahashi H, Kenmochi T, Shiroki H, Hoshinaga K. The Combined Predictive Value of the ECD Criteria for Long-term Graft Survival of Kidneys from Donors after Cardiac Death: A Single-center Experience from over Three Decades. Int j Urol 2016; 23(4): 319-24.
  19. Sato H, Maeda K, Kotake K, Sugihara K, Takahashi H. Factors affecting recurrence and prognosis after R0 resection for colorectal cancer with peritoneal metastasis. J Gastroenterol 2016; 51(5): 465-72.
  20. Ishii H, Aoyama T, Takahashi H, Kumada Y, Kamoi D, Sakakibara T, Umemoto N, Suzuki S, Tanaka A, Ito Y, Murohara T. Treatment with cilostazol improves clinical outcome after endovascular therapy in hemodialysis patients with peripheral artery disease. J Cardiol 2016; 67(2): 199-204.
  21. Ozuno NT, Akamatsu H, Takahashi H, Fujii N, Yoshida S. Quantitative diagnosis of connective tissue disease-associated interstitial pneumonia using thoracic computed tomography images. Clin Rheumatol. 2015; 34 (12): 2113-8.
  22. Motoyama S, Ito H, Sarai M, Kondo T, Kawai H, Nagahara Y, Harigaya H, Kan S, Anno H, Takahashi H, Naruse H, Ishii J, Hecht H, Shaw LJ, Ozaki Y, Narula J. Plaque Characterization by Coronary Computed Tomography Angiography and the Likelihood of Acute Coronary Events in Mid-Term Follow-Up. J Am Coll Cardiol 2015; 66(4): 337-46.
  23. Ando Y, Hayashi T, Ito K, Suzuki E, Mine N, Miyamoto A, Oya M, Matsuda H, Isaji A, Nakanishi T, Imaizumi K, Shibata T, Okada T, Sakurai K, Naito K, Uyama I, Kawada K, Takahashi H, Yamada S. Comparison between 5-day aprepitant and single-dose fosaprepitant meglumine for preventing nausea and vomiting induced by cisplatin-based chemotherapy. Support Care Cancer. 2015 Jul 25.
  24. Kitaguchi N, Hasegawa M, Ito S, Kawaguchi K, Hiki Y, Nakai S, Suzuki N, Shimano Y, Ishida O, Kushimoto H, Kato M, Koide S, Kanayama K, Kato T, Ito K, Takahashi H, Mutoh T, Sugiyama S, Yuzawa Y. A prospective study on blood Aβ levels and the cognitive function of patients with hemodialysis: a potential therapeutic strategy for Alzheimer's disease. J Neural Transm. 2015; 122(11): 1593-607.
  25. Sasaki H, Suzuki A, Kusaka M, Fukami N, Shiroki R, Itoh M, Takahashi H, Uenishi K, Hoshinaga K. Nutritional Status in Japanese Renal Transplant Recipients With Long-term Graft Survival. Transplant Proc 2015; 47(2): 367-72.
  26. Ishii J, Takahashi H, Kitagawa F, Kuno A, Okuyama R, Kawai H, Muramatsu T, Naruse H, Motoyama S, Matsui S, Hasegawa M, Aoyama T, Kamoi D, Kasuga H, Izawa H, Ozaki Y, Yuzawa Y. Multimarker approach to risk stratification for long-term mortality in patients on chronic hemodialysis. Circ J 2015; 79 (3): 656-63.
  27. Shiino K, Sugimto K, Yamada A, Takada K, Kawai H, Sugimoto K, Takahashi H, Takagi Y, Iwase M, Ozaki Y. Usefulness of Right Ventricular Basal Free Wall Strain by Two-Dimensional Speckle Tracking Echocardiography in Patients With Chronic Thromboembolic Pulmonary Hypertension. Int Heart J 2015; 56 (1): 1-5.
  28. Ozaki Y, Kawai T, Ismail TF, Ohta M, Okumura M, Takahashi H, Muramatsu T, Umeda H, Murohara T. Fate and clinical significance of angiographically visible stent malapposition (peri-stent contrast staining) after drug-eluting stent implantation: a long-term clinical follow-up study. Asian Intervention 2015; 1: 48-56.
  29. Suzuki A, Ando H, Takashima H, Kumagai S, Kurita A, Waseda K, Suzuki Y, Mizuno T, Harada K, Uetani T, Takahashi H, Yoshikawa D, Ishii H, Murohara T, Amano T. Effects of polyunsaturated fatty acids on periprocedural myocardial infarction after elective percutaneous coronary intervention. EuroIntervention. 2014; 10 (7): 792-8.
  30. Hayashi T, Ikehata S, Matsuzaki H, Yasuda K, Makihara T, Futamura A, Arakawa Y, Kuki R, Fukuura K, Takahashi H, Mori N, Higashiguchi T, Yamada S. Influence of Serum Albumin Levels during Opioid Rotation from Morphine or Oxycodone to Fentanyl for Cancer Pain. Biol Pharm Bull. 2014; 37 (12): 1860-5.
  31. Kumada Y, Nogaki H, Ishii H, Aoyama T, Kamoi D, Takahashi H, Murohara T. Clinical outcome after infrapopliteal bypass surgery in chronic hemodialysis patients with critical limb ischemia. J Vasc Surg 2015; 61(2): 400-4.
  32. Kawai H, Motoyama S, Sarai M, Ito H, Takahashi H, Harigaya H, Kan S, Ishii J, Anno H, Murohara T, Ozaki Y. Adding coronary computed tomography angiography to invasive coronary angiography improves prediction of cardiac events. Circ J. 2014; 78 (11): 2735-40.
  33. Kawai H, Watanabe E, Yamamoto M, Harigaya H, Sano K, Takatsu H, Muramatsu T, Naruse H, Sobue Y, Motoyama S, Sarai M, Takahashi H, Arakawa T, Kan S, Sugiura A, Murohara T, Ozaki Y. Major bleeding complications related to combined antithrombotic therapy in atrial fibrillation patients 12 months after coronary artery stenting. J Cardiol 2015; 65(3): 197-202.
  34. Kumada Y, Ishii H, Aoyama T, Kamoi D, Kawamura Y, Sakakibara T, Nogaki H, Takahashi H, Murohara T. Long-Term Clinical Outcome after Surgical or Percutaneous Coronary Revascularization in Hemodialysis Patients. Circ J 2013; 78 (4): 986-92.
  35. Hasegawa M, Ishii J, Kitagawa F, Takahashi H, Kanayama K and Yuzawa Y. Urinary neutrophil gelatinase-associated lipocalin as a biomarker of cardiovascular events in chronic kidney disease. Heart Vessels 2015; 30(1): 81-8.
  36. Takahashi H, Ito Y, Ishii H, Aoyama T, Kamoi D, Kasuga H, Yasuda K, Maruyama S, Matsuo S, Murohara T, Yuzawa Y. Geriatric Nutritional Risk Index Accurately Predicts Cardiovascular Mortality in Incident Hemodialysis Patients. J Cardiol 2014; 64 (1): 32-6.
  37. Kawai H, Sarai M, Motoyama S, Ito H, Takada K, Harigaya H, Takahashi H, Hashimoto S, Takagi Y, Ando M, Anno H, Ishii J, Murohara T, Ozaki Y. A combination of anatomical and functional evaluations improves the prediction of cardiac event in patients with coronary artery bypass. BMJ Open. 2013; 3(11).
  38. Ito H, Motoyama S, Sarai M, Kawai H, Harigaya H, Kan S, Kato S, Anno H, Takahashi H, Naruse H, Ishii J, Narula J, Ozaki Y. Characteristics of plaque progression detected by serial coronary computed tomography angiography. Heart Vessels. 2014; 29 (6): 743-9.
  39. Ishii H, Aoyama T, Takahashi H, Kamoi D, Tanaka M, Yoshikawa D, Hayashi M, Matsubara T, Murohara T. Serum albumin and C-reactive protein levels predict clinical outcome in hemodialysis patients undergoing endovascular therapy for peripheral artery disease. Atherosclerosis 2013; 227(1): 130-4.
  40. Takahashi H, Ishii H, Aoyama T, Kamoi D, Kasuga H, Ito Y, Yasuda K, Tanaka M, Yoshikawa D, Maruyama S, Matsuo S, Murohara T, Yuzawa Y. Association of Cardiac Valvular Calcifications and C-Reactive Protein With Cardiovascular Mortality in Incident Hemodialysis Patients: A Japanese Cohort Study. Am J Kidney Dis 2013; 61(2): 254-61.
  41. Hasegawa M, Ishii J, Kitagawa F, Kanayama K, Takahashi H, Ozaki Y, Yuzawa Y. Prognostic value of highly sensitive troponin T on cardiac events in patients with chronic kidney disease not on dialysis. Heart Vessels 2013; 28(4): 473-9.
  42. Kamoi D, Ishii H, Takahashi H, Aoyama T, Toriyama T, Tanaka M, Kawamura Y, Kawashima K, Yoshikawa D, Amano T, Uetani T, Matsubara T, Murohara T. Sirolimus- vs. paclitaxel-eluting stent to coronary intervention in dialysis patients. Int J Cardiol. 2013; 165(3): 533-6.
  43. Takahashi R, Ito Y, Takahashi H, Ishii H, Kasuga H, Mizuno M, Suzuki Y, Yuzawa Y, Maruyama S, Murohara T, Imai E, Matsuo S. Combined values of serum albumin, C-reactive protein and body mass index at dialysis initiation accurately predicts long-term mortality. Am J Nephrol 2012; 36 (2): 136-43.
  44. Suzuki M, Takahashi H, Aoyama T, Tanaka M, Ishii H, Kisohara M, Iizuka N, Murohara T, Hayano J. Nonlinear measures of heart rate variability and mortality risk in hemodialysis patients. Clin J Am Soc Nephrol 2012; 7 (9): 1454-60.
  45. Kobayashi T, Mori Y, Tsugawa T, Hashizume C, Takahashi H. Prognostic factors for tumor recurrence after gamma knife radiosurgery of partially resected and recurrent craniopharyngiomas. Nagoya J Med Sci 2012; 74 (1-2): 141-7.
  46. Ishii H, Toriyama T, Aoyama T, Takahashi H, Tanaka M, Yoshikawa D, Hayashi M, Kasuga H, Yasuda Y, Maruyama S, Matsubara T, Matsuo S, Murohara T. Percutaneous Coronary Intervention with Bare Metal Stent vs. Drug-Eluting Stent in Hemodialysis Patients. Circ J 2012; 76 (7): 1609-15.
  47. Ishii H, Kumada Y, Takahashi H, Toriyama T, Aoyama T, Tanaka M, Yoshikawa D, Hayashi M, Kasuga H, Yasuda Y, Maruyama S, Matsubara T, Matsuo S, Murohara T. Impact of diabetes and glycemic control on peripheral artery disease in Japanese patients with end-stage renal disease –Long-term follow-up study from beginning of haemodialysis. Diabetologia 2012; 55: 1304-09.
  48. Sakakibara T, Ishii H, Toriyama T, Aoyama T, Takahashi H, Kamoi D, Kawamura Y, Kawashima K, Yoneda K, Amano T, Tanaka M, Yoshikawa D, Hayashi M, Matsubara T, Murohara T. Sirolimus-Eluting Stent vs. Everolimus-Eluting Stent for Coronary Intervention in Patients on Chronic Hemodialysis. Circ J. 2012; 76 (2): 351-55.
  49. Tanaka M, Ishii H, Aoyama T, Takahashi H, Toriyama T, Kasuga H, Takeshita K, Yoshikawa D, Amano T, Murohara T. Ankle brachial pressure index but not brachial-ankle pulse wave velocity is a strong predictor of systemic atherosclerotic morbidity and mortality in patients on maintenance hemodialysis. Atherosclerosis. 2011; 219 (2): 643-7.
  50. Hayashi M, Shibata R, Takahashi H, Ishii H, Aoyama T, Kasuga H, Yamada S, Ohashi K, Maruyama S, Matsuo S, Ouchi N, Murohara T, Toriyama T. Association of adiponectin with carotid arteriosclerosis in predialysis chronic kidney disease. Am J Nephrol. 2011; 34 (3): 249-55.
  51. Ishii H, Nishio M, Takahashi H, Aoyama T, Tanaka M, Toriyama T, Tamaki T, Yoshikawa D, Hayashi M, Amano T, Matsubara T, Murohara T. Comparison of atorvastatin 5 and 20 mg/d for reducing F-18 fluorodeoxyglucose uptake in atherosclerotic plaques on positron emission tomography/computed tomography: a randomized, investigator-blinded, open-label, 6-month study in Japanese adults scheduled for percutaneous coronary intervention. Clin Ther. 2010; 32 (14): 2337-47.
  52. Kojima M, Hayano J, Suzuki S, Seno H, Kasuga H, Takahashi H, Toriyama T, Kawahara H, Furukawa TA. Depression, alexithymia and long-term mortality in chronic hemodialysis patients. Psychother Psychosom. 2010; 79 (5): 303-11.
  53. Ishii H, Kumada Y, Toriyama T, Aoyama T, Takahashi H, Murohara T. Prognostic values of C-reactive protein levels on clinical outcome after endovascular therapy in hemodialysis patients with peripheral artery disease. J Vasc Surg. 2010; 52 (4): 854-9.
  54. Yamada S, Ishii H, Takahashi H, Aoyama T, Morita Y, Kasuga H, Kimura K, Ito Y, Takahashi R, Toriyama T, Yasuda Y, Hayashi M, Kamiya H, Yuzawa Y, Maruyama S, Matsuo S, Matsubara T, Murohara T. Prognostic value of reduced left ventricular ejection fraction at start of hemodialysis therapy on cardiovascular and all-cause mortality in end-stage renal disease patients. Clin J Am Soc Nephrol. 2010; 5 (10): 1793-8.
  55. Ishii H, Kumada Y, Toriyama T, Aoyama T, Takahashi H, Tanaka M, Kamoi D, Kawamura Y, Yamada S, Hayashi M, Yasuda Y, Yuzawa Y, Maruyama S, Matsuo S, Matsubara T, Murohara T Effects of oral cilostazol 100 mg BID on long-term patency after percutaneous transluminal angioplasty in patients with femoropopliteal disease undergoing hemodialysis: a retrospective chart review in Japanese patients. Clin Ther. 2010; 32 (1): 24-33.
  56. Imai N, Takeda K, Kuzuya T, Utsunomiya S, Takahashi H, Kasuga H, Asai M, Yamada M, Tanikawa Y, Goto H. High incidence of colonic perforation during colonoscopy in hemodialysis patients with end-stage renal disease. Clin Gastroenterol Hepatol. 2010; 8 (1): 55-9.
  57. Ishii H, Toriyama T, Aoyama T, Takahashi H, Amano T, Hayashi M, Tanaka M, Kawamura Y, Yasuda Y, Yuzawa Y, Maruyama S, Matsuo S, Matsubara T, Murohara T. Prognostic values of C-reactive protein levels on clinical outcome after implantation of sirolimus-eluting stents in patients on hemodialysis. Circ Cardiovasc Interv. 2009; 2 (6): 513-8.
  58. Kawamura Y, Ishii H, Aoyama T, Tanaka M, Takahashi H, Kumada Y, Toriyama T, Murohara T. Nitinol stenting improves primary patency of the superficial femoral artery after percutaneous transluminal angioplasty in hemodialysis patients: a propensity-matched analysis. J Vasc Surg. 2009; 50 (5): 1057-62.
  59. Ishii H, Kumada Y, Toriyama T, Aoyama T, Takahashi H, Amano T, Yasuda Y, Yuzawa Y, Maruyama S, Matsuo S, Matsubara T, Murohara T. Aortic valvular calcification predicts restenosis after implantation of drug-eluting stents in patients on chronic haemodialysis. Nephrol Dial Transplant. 2009; 24 (5): 1562-7.
  60. Maruyama S, Taguchi A, Iwashima S, Ozaki T, Yasuda K, Kikuchi-Taura A, Soma T, Ishii H, Murohara T, Takahashi H, Kasuga H, Kumada Y, Toriyama T, Ito Y, Kawahara H, Yuzawa Y, Matsuo S. Low circulating CD34+ cell count is associated with poor prognosis in chronic hemodialysis patients. Kidney Int. 2008; 74 (12): 1603-9.
  61. Ishikawa T, Takeda K, Itoh M, Imaizumi T, Oguri K, Takahashi H, Kasuga H, Toriyama T, Matsuo S, Hirooka Y, Itoh A, Kawashima H, Kasugai T, Ohno E, Miyahara R, Ishigami M, Katano Y, Ohmiya N, Niwa Y, Goto H. Prevalence of pancreatic cystic lesions including intraductal papillary mucinous neoplasms in patients with end-stage renal disease on hemodialysis. Pancreas. 2009; 38 (2): 175-9.
  62. Kumada Y, Aoyama T, Ishii H, Tanaka M, Kawamura Y, Takahashi H, Toriyama T, Aoyama T, Yuzawa Y, Maruyama S, Matsuo S, Murohara T. Long-term outcome of percutaneous transluminal angioplasty in chronic haemodialysis patients with peripheral arterial disease. Nephrol Dial Transplant. 2008; 23 (12): 3996-4001.
  63. Ishii H, Kumada Y, Toriyama T, Aoyama T, Takahashi H, Yamada S, Yasuda Y, Yuzawa Y, Maruyama S, Matsuo S, Matsubara T, Murohara T. Cilostazol improves long-term patency after percutaneous transluminal angioplasty in hemodialysis patients with peripheral artery disease. Clin J Am Soc Nephrol. 2008; 3 (4): 1034-40.
  64. Aoyama T, Ishii H, Toriyama T, Takahashi H, Kasuga H, Murakami R, Amano T, Uetani T, Yasuda Y, Yuzawa Y, Maruyama S, Matsuo S, Matsubara T, Murohara T. Sirolimus-eluting stents vs bare metal stents for coronary intervention in Japanese patients with renal failure on hemodialysis. Circ J. 2008; 72 (1): 56-60.
  65. Ishii H, Toriyama T, Aoyama T, Takahashi H, Yamada S, Kasuga H, Ichimiya S, Kanashiro M, Mitsuhashi H, Maruyama S, Matsuo S, Naruse K, Matsubara T, Murohara T. Efficacy of oral nicorandil in patients with end-stage renal disease: a retrospective chart review after coronary angioplasty in Japanese patients receiving hemodialysis. Clin Ther. 2007; 29 (1): 110-22.
  66. Yasuda K, Kasuga H, Aoyama T, Takahashi H, Toriyama T, Kawade Y, Iwashima S, Yamada S, Kawahara H, Maruyama S, Yuzawa Y, Ishii H, Murohara T, Matsuo S. Comparison of percutaneous coronary intervention with medication in the treatment of coronary artery disease in hemodialysis patients. J Am Soc Nephrol. 2006; 17 (8): 2322-32.
  67. Kitano Y, Kasuga H, Watanabe M, Takahashi H, Ibuki K, Kawade Y, Yasuda K, Iwashima S, Toriyama T, Matuo S, Kawahara H. Severe coronary stenosis is an important factor for induction and lengthy persistence of ventricular arrhythmias during and after hemodialysis. Am J Kidney Dis. 2004; 44 (2): 328-36.
  68. Fukuta H, Hayano J, Ishihara S, Sakata S, Ohte N, Takahashi H, Yokoya M, Toriyama T, Kawahara H, Yajima K, Kobayashi K, Kimura G. Prognostic value of nonlinear heart rate dynamics in hemodialysis patients with coronary artery disease. Kidney Int. 2003; 64 (2): 641-8.
  69. Liu M, Takahashi H, Morita Y, Maruyama S, Mizuno M, Yuzawa Y, Watanabe M, Toriyama T, Kawahara H, Matsuo S. Non-dipping is a potent predictor of cardiovascular mortality and is associated with autonomic dysfunction in haemodialysis patients. Nephrol Dial Transplant. 2003; 18 (3): 563-9.
  70. Toriyama T, Kumada Y, Matsubara T, Murata A, Ogino A, Hayashi H, Nakashima H, Takahashi H, Matsuo H, Kawahara H. Effect of artificial carbon dioxide foot bathing on critical limb ischemia (Fontaine IV) in peripheral arterial disease patients. Int Angiol. 2002; 21 (4): 367-73.
  71. Toriyama T, Yokoya M, Nishida Y, Kawajiri K, Takahashi H, Kawahara H. Increased incidence of coronary artery disease and cardiac death in elderly diabetic nephropathy patients undergoing chronic hemodialysis therapy. J Cardiol. 2000; 36 (3): 165-71.
  72. Hayano J, Takahashi H, Toriyama T, Mukai S, Okada A, Sakata S, Yamada A, Ohte N, Kawahara H. Prognostic value of heart rate variability during long-term follow-up in chronic haemodialysis patients with end-stage renal disease. Nephrol Dial Transplant. 1999; 14 (6): 1480-8.
  73. Takahashi H, Matsuo S, Toriyama T, Kawahara H, Hayano J. Autonomic dysfunction in hemodialysis patients with persistent hypotension. Nephron. 1996; 72 (3): 418-23.
  74. Toriyama T, Matsuo S, Fukatsu A, Takahashi H, Sato K, Mimuro N, Kawahara H. Effects of high-dose vitamin B6 therapy on microcytic and hypochromic anemia in hemodialysis patients. Nippon Jinzo Gakkai Shi. 1993; 35 (8): 975-80.