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Œ¤‹†ŽÒƒf[ƒ^ƒx[ƒX
–¼‘OF ‘å] Œ«Ž¡(Kenji Ohe)
Œ¤‹†•ª–ì‚ÌKeywordF ˆâ“`Žq”­Œ»‹@\
ƒz[ƒ€ƒy[ƒWF http://researchmap.jp/ohekenji/
“dŽqƒ[ƒ‹ƒAƒhƒŒƒXF oekenji@fujita-hu.ac.jp
Žæ“¾Ž‘ŠiF ˆãŽt–Æ‹–@1991”N
“à‰È”F’èˆã@2005”N
“à•ª”åê–åˆã@2007”N
‚»‚Ì‘¼F http://www2.hp-ez.com/hp/kenjisplicing/page1

http://groups.google.co.jp/group/splicing?hl=ja

Œ¤‹†•ª–ìî•ñ (#1)
Œ¤‹†•ª–ì-1F ˆâ“`Žq”­Œ»‹@\
Œ¤‹†‰Û‘è-1F mRNA‘O‹ì‘̃Xƒvƒ‰ƒCƒVƒ“ƒO‚Ì‹@\
‘I‘ð“IƒXƒvƒ‰ƒCƒVƒ“ƒO‚Ì’²ßE§Œä
ƒXƒvƒ‰ƒCƒVƒ“ƒOˆÙíŽ¾Š³‚Ì•a—
HMG’`”’‚ƃXƒvƒ‰ƒCƒVƒ“ƒO‚ÌŠÖ˜A«

Š‘®‹@ŠÖ/‘gD (#1)
Š‘®‹@ŠÖ–¼-1F “¡“c•ÛŒ’‰q¶‘åŠw
Š‘®•”–¼(1) 1F ‘‡ˆã‰ÈŠwŒ¤‹†Š
Š‘®•”–¼(2) 1F ˆâ“`Žq”­Œ»‹@\Œ¤‹†•”–å
–ðEEE–¼-1F y‹³Žö
—X•Ö”ԍ†-1F 470-1192
ZŠ-1F ˆ¤’mŒ§–L–¾ŽsŒBŠ|’¬“cŠyƒ–ŒE1-98

Š‘®Šw‰ï^Œ¤‹†‰ï (#1)
Š‘®Šw‰ï–¼-1F “ú–{“à•ª”åŠw‰ï
Š‘®Šw‰ï^Œ¤‹†‰ï (#2)
Š‘®Šw‰ï–¼-2F “ú–{“à‰ÈŠw‰ï
Š‘®Šw‰ï^Œ¤‹†‰ï (#3)
Š‘®Šw‰ï–¼-3F “ú–{RNAŠw‰ï
Š‘®Šw‰ï^Œ¤‹†‰ï (#4)
Š‘®Šw‰ï–¼-4F “ú–{bó‘BŠw‰ï
Š‘®Šw‰ï^Œ¤‹†‰ï (#5)
Š‘®Šw‰ï–¼-5F “ú–{“œ”A•aŠw‰ï
Š‘®Šw‰ï^Œ¤‹†‰ï (#6)
Š‘®Šw‰ï–¼-6F “ú–{•ªŽq¶•¨Šw‰ï

Œ¤‹†—ð^ŽÀÑ [1996”N] (#3)
Papers-3F Ohe K, Ikuyama S, Takayanagi R, Kohn LD, Nawata H. Interferon-gamma suppresses thyrotropin receptor promoter activity by reducing thyroid transcription factor-1 (TTF-1) binding to its recognition site.Mol Endocrinol. 1996 Jul;10(7):826-36.
Œ¤‹†—ð^ŽÀÑ [2000”N] (#7)
Papers-7F Ohe K, Lalli E, Sassone-Corsi P. A direct role of SRY and SOX proteins in pre-mRNA splicing. Proc Natl Acad Sci U S A. 2002 Feb 5;99(3):1146-51.
Œ¤‹†—ð^ŽÀÑ [2007”N] (#14)
Papers-14F Ohe K, Manabe T (K.O and T.M equal contribution), Katayama T, Matsuzaki S, Yanagita T, Okuda H, Bando Y, Imaizumi K, Reeves R, Tohyama M, Mayeda A. HMGA1a: sequence-specific RNA-binding factor causing sporadic Alzheimer s disease-linked exon skipping of presenilin-2 pre-mRNA. Genes Cells. 2007 Oct;12(10):1179-91.
Œ¤‹†—ð^ŽÀÑ [2009”N] (#16)
Papers-16F Ohe K, Tamai KT, Parvinen M, Sassone-Corsi P.
DAX-1 and SOX6 molecular interplay results in an antagonistic effect in pre-mRNA splicing.
Dev Dyn. 2009 Jun;238(6):1595-604.

Kenji Ohe and Akila Mayeda.
HMGA1a Trapping of U1 snRNP at Authentic 5 Splice Site Induces Aberrant Exon Skipping in Sporadic Alzheimer"s Disease.
Mol.Cell.Biol. 2010 in press
Œ¤‹†—ð^ŽÀÑ [2010”N] (#17)
Papers-17F Kenji Ohe and Akila Mayeda. HMGA1a Trapping of U1 snRNP at Authentic 5!#%ap!#% Splice Site Induces Aberrant Exon Skipping in Sporadic Alzheimer"s Disease. Mol.Cell.Biol. 30:2220-2228, 2010 (selected as spotlight http://mcb.asm.org/cgi/content/short/30/9/2075

Wed Dec 29 13:46:28 JST 2010

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