業 績



1.Differentiation of cancer from atrial fibrillation in patients with acute multifocal stroke Ito S, Ueda A, Murate K, Hirota S, Fukui T, Ishikawa T, Shima S, Hikuchi C, Mizutani Y, Kizawa M, Asakura K, Mutoh T. J Neurol Sci   368 344-348

2.Magnetic resonance neurography for the evaluation of CIDP Ishikawa T, Asakura K, Mizutani Y, Ueda A, Murate K, Hikichi C, Shima S, Kizawa M, Komori M, Murayama K, Toyama H, Ito S, Mutoh T. Muscle Nerve  

3.Hypertrophic Cardiomyopathy Accompanied by Spinocerebellar Atrophy with a Novel Mutation in Troponin ⅠGene  Kawai H, Morimoto S, Takakuwa Y, Ueda A, Inada K, Sarai M, Arimura T, Mutoh T, Kimura A, Ozaki Y. Int Heart J   57(4) 507-10

4.Phase Ⅱ Trial of Intravenous Low-Dose Granulocyte Colony-Stimulating Factor in Acute Ischemic Stroke Mizuma A, Yamashita T, Kono S, Nakayama T, Baba Y, Itoh S, Asakura K, Niimi Y, Asahi T, Kanemaru K, Mutoh T, Kuroda S, Kinouchi H, Abe K, Takizawa S. J Stroke Cerebrovasc Dis   25(6) 145-147

5.Case of limbic encephalitis with anti-neutral glycosphingolipid antibodies Takeuchi Y, Ueda M, Ochiai J, Mabuchi C, Shima S, Mutoh T. Neurol Clin Neurosci   4(2) 70-72

6.Relapsing polychondritis-associated limbic encephalitis preceding the emergence of systemic inflammation Kawabe M, Tachi R, Hideyama T, Yagi M, Kishida Y, Maekawa R, Shima S, Mutoh T, Shiio Y. Neurol Clin Neurosci   4(4) 162-164

7.Muscle MRI of the Upper Extremity in the Myotonic DystrophyType 1 Hayashi K, Hamano T, Kawamura Y, Kimura H, Matsunaga A, Ikawa M, Yamamura O, Mutoh T, Higuchi I, Kuriyama M, Nakamoto Y. Eur Neurol   76(1-2) 87-94

8.Depressive state as an initial symptom for subdural abscess. Fukui T, Ueda A, Murate K-I, Hikichi C, Ito S, Asakura K, Mutoh T. Neurol Clin Neurosci   4(1) 31-33





1. Fukuda Y, Fukui T, Hikichi C, Ishikawa T, Murate K, Adachi T, Imai H, Fukuhara K, Ueda A, Kaplan AP, Mutoh T. Neurotropin promotes NGF signaling through interaction of GM1 ganglioside with Trk neurotrophin receptor in PC12 cells. Brain Res 1596: 13-21, 2015

2. Asakura K, Ueda A, Mutoh T. Lipid rafts and their possible involvements in neuroimmunological disorders. Front Biosci (Landmark Ed) 20: 303-313, 2015

3. Hirota S, Ito S, Fukui T, Murate K, Shima S, Kizawa M, Ueda A, Asakura K, Mutoh T. Voriconazole-responsive disseminated nodular lesions on spinal MRI. Intern Med 54: 215-218, 2015

4. Nakamura K, Sugaya K, Nakata Y, Shima S, Mutoh T, Nakano I. Hypertrophic pachymeningitis and encephalitis in a patient with relapsing polychondritis. Neurol Clin Neurosci 3: 42-43, 2015

5. Fukui T, Asakura K, Hikichi C, Ishikawa T, Murai R, Hirota S, Murate KI, Kizawa M, Ueda A, Ito S, Mutoh T. Histone deacetylase inhibitor attenuates neurotoxicology of clioquinol in PC12 cells. Toxicology: Epub ahead of print, 2015

6. Hikichi C, Asakura K, Hirota S, Murate K, Ishikawa T, Kizawa M, Ueda A, Ito S, Mutoh T. Deep neck inflammatry diseases: implication of cervical magnetic resonance imaging for early diagnosis. Austin J Clin Neurol: in press, 2015



1. 木澤真努香、水谷泰彰、武藤多津郎 神経内科研修ノート 腎疾患に伴う神経系疾患 永井良三他編集 p429-431, 診断と治療社, 2015





1. Shima S, Kawamura N, Ishikawa T, Masuda H, Iwahara C, Niimi Y, Ueda A, Iwabuchi K, Mutoh T. Anti-neutral glycolipid antibodies in encephalomyeloradiculoneuropathy. Neurology 82: 114-118, 2014

2. Ikeda M, Miki T, Atsumi M, Inagaki A, Mizuguchi E, Meguro M, Kanamori D, Nakagawa K, Watanabe R, Mano K, Aihara A, Hane Y, Mutoh T, Matsuo K. Effective elimination of contaminants after oral care in elderly institutionalized individuals. Geriatr Nurs 35: 295-299, 2014

3. Asakura K, Ueda A, Shima S, Ishikawa T, Hikichi C, Hirota S, Fukui T, Ito S, Mutoh T. Targeting of aquaporin 4 into lipid rafts and its biological significance. Brain Res 1583: 237-244, 2014

4. Uemura N, Sugano K, Hiraishi H, Shimada K, Goto S, Uchiyama S, Okada Y, Origasa H, Ikeda Y, Mutoh T, et al. Risk factor profiles, drug usage, and prevalence of aspirin-associated gastroduodenal injuries among high-risk cardiovascular Japanese patients: the results from the MAGIC study. J Gastroenterol 49: 814-824.

5. Mutoh T. Emergence of new roles of lipid rafts in neurological disorders. J Neurol Transl Neurosci 1: 2-3, 2013

6. Kato M, Kawaguchi K, Ito S, Mutoh T, Kitaguchi N, et al.  Potential therapeutic system for Alzheimer's disease: removal of blood Aβs by hemodialzyers and its effect on the cognitive functions of renal-failure patients. J Neural Transm 119: 1533-1544, 2012

7. Kawamura N, Kizawa M, Ueda A, Niimi Y, Mutoh T. An update on diagnostic imaging studies of viral encephalitis. Future Virol 7: 901-909, 2012

8. Hamano T, Mutoh T, Hirayama M, et al.  Winged scapula in patients with myotonic dystrophy type 1. Neuromusc Disord 22: 755-758, 2012

9. Mutoh T, Kawamura N, Hirabayashi Y, Shima S, Miyashita T, Ito S, Asakura K, Muto E, Masserini M et al.  Abnormal cross-talk between mutant presenilin 1 (I143T, G384A) and glycosphingolipid biosynthesis. FASEB J 26: 3065-3074, 2012

10. Kitaguchi N, Kawaguchi K, Nakai S, Murakami K, Ito S, Hoshino H, Hori H, Ohashi A, Shimano Y, Suzuki N, Yuzawa Y, Mutoh T, Sugiyama S.: Reduction of Alzheimer's Disease Amyloid-β in Plasma by Hemodialysis and Its Relation to Cognitive Functions. Blood Purif 32: 57-62, 2011

11. Kawamura Y, Sugata K, Ihira M, Mihara T, Mutoh T, Asano Y, Yoshikawa T. Different characteristics of human herpesvirus 6 encephalitis between primary infection and viral reactivation. J Clin Virol 51 :12-19, 2011

12. Kizawa-Ueda M, Ueda A, Kawamura N, Ishikawa T, Mutoh E, Fukuda Y, Shiroki R, Hoshinaga K, Ito S, Asakura K, Mutoh T: Neuroptophin levels in cerebroppinal fluid of adult patients with meningitis and encephalitis. Eur Neurol 65: 138-143, 2011

13. Ito S, Shima S, Ueda A, Kawamura N, Asakura K, Mutoh T: Transient splenial lesion of the corpus callosum in H1N1 influenza virus-associated encephalitis/encephalopathy. Int Med 50: 915-918, 2011

14. Origasa H, Goto S, Shimada K, Uchiyama S, Okada Y, Sugano K, Hiraishi H, Uemura N, Ikeda Y; MAGIC Investigators. Collaborators: Asakura K, Mutoh T et al. Prospective cohort study of gastrointestinal complications and vascular diseases in patients taking aspirin: rationale and design of the MAGIC Study. Cardiovasc Drugs Ther. 2011;6:551-60, 2011

15. Ueda A, Shima S, Miyashita T, Ito S, Ueda M, Kusunoki S, Asakura K, Mutoh T: Anti-GM1 antibodies affect the integrity of lipid rafts. Mol. Cell Neurosci 45: 355-362, 2010.

16. Fukuda Y, Berry TL, Nelson M, Hunter CL, Fukuhara K, Imai H, Ito S, Granholm-Bentley AC, Kaplan AP, Mutoh T: Stimulated neuronal expression of brain-derived neurotrophic factor by Neurotropin. Mol Cell Neurosci 45:226-233, 2010

17. Kawaguchi K, Kitaguchi N, Nakai S, Murakami K, Asakura K, Mutoh T, Fujita Y, Sugiyama S: Novel therapeutic approach for Alzheimer’s disease by removing amyloid beta protein form the brain with an extracorporeal removable system. J. Artif. Organs 13: 31-37, 2010.

18. Hara H, Kataoka S, Anan M, Ueda A, Mutoh T, Tabira T.: The therapeutic effects of the herbal medicine, Juzen-taiho-to, on amyloid-beta burden in a mouse model of Alzheimer's disease. J Alzheimers Dis. 20:427-439, 2010

19. Hamano T, Kawamura Y, Mutoh T, Hirayama M, Kuriyama M.: Muscle MRI in myotonic dystrophy type 1 with foot drop. Eur Neurol 63:144-148, 2010



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5. 島さゆり、木澤真努香、宮下忠行、朝倉邦彦、武藤多津郎 単純ヘルペス脳炎後に広汎な大脳白質病変をきたした1例 神経治療学 27:567-572, 2010

6. 井水秀栄、加藤庸子、森田功、伊藤圭介、島さゆり、清水康裕、佐野公俊、廣瀬雄一、鈴木伸行、奥寺敬、毛受淳一 脳卒中初期診療における教育コース開催による多種連携の効果について Neurosurg Emerg. 15: 109-115, 2010



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