Case 35. 

Crohn-like longitudinal colonic ulcer in chronic granulomatous disease (8 y-o M)
       
  Colon surgically resected for intractable ulceration seen in chronic granulomatous disease  
       

 

  Chronic granulomatous disease is characterized by hereditary neutrophilic dysfunction. The defective neutrophils cannot digest catalase-producing microbes, such as Staphylococcus, E. coli, tuberculous bacilli and fungi.