AMERICAN JOURNAL OF TRANSPLANTATION 12(4) 867-876 2012年4月
Using a murine model, we demonstrated that endobronchial administration of antibodies (Abs) to major histocompatibility complex (MHC) class I results in cellular infiltration, epithelial metaplasia, fibrosis and obstruction of the small airways (o...
Introduction: Mizoribine (MZR) is an inosine monophosphate dehydrogenase inhibitor. It has been widely used in Japan in the treatment of autoimmune diseases and is known to inhibit T and B cell proliferation. The aim of this study was to evaluate ...
Naohiko Fukami   Sabarinathan Ramachandran   Kishore Narayanan   Wei Liu   Dilip S. Nath   Martin Jendrisak   William Chapman   Thalachallour Mohanakumar   
TRANSPLANTATION 93(4) 364-372 2012年2月
Background. Presence of donor-specific antibodies (Abs) is detrimental to posttransplant allograft function. Some sensitized recipients have successfully undergone transplantation after pretransplant conditioning regimen using plasmapheresis and/o...
Inflammatory insults following islet transplantation (ITx) hinders engraftment and long-term function of the transplanted (Tx) islets. Using a murine model of ITx, we determined the role of LMP-420, a novel TNF-alpha inhibitor, both individually a...