A long-term high-fat diet (HFD) causes obesity and changes in renal lipid metabolism and lysosomal dysfunction in mice, causing renal damage. Sodium-glucose co-transporter inhibitors, including phlorizin, exert nephroprotective effects in patients...
Kyongtae T Bae   Kanako Kumamoto   Aya Yoshimura   Masanori Kugita   Shigeo Horie   Tamio Yamaguchi   Junu T Bae   Shizuko Nagao   
Journal of nephrology 35(3) 1033-1040 2021年11月 [査読有り]
BACKGROUND: Cystogenesis in polycystic kidney disease (PKD) is likely accelerated by various renal insults, including crystal deposition, that activate renal tubule obstruction and dilation. We developed a capsule-based device that can be applied ...
The Journal of general virology 102(4) 2021年4月 [査読有り]
With the recent establishment of robust reverse genetics systems for rotavirus, rotavirus is being developed as a vector to express foreign genes. However, insertion of larger sequences such as those encoding multiple foreign genes into the rotavi...
JOURNAL OF NUTRITIONAL SCIENCE AND VITAMINOLOGY 67(4) 243-248 2021年 [査読有り]
Daily fat and sugar intake has increased in Japan, while total energy intake has decreased. However, the number of type 2 diabetes mellitus patients has increased, and this often causes renal injury characterized by autophagic vacuoles. Although m...