医学部

研究分野

ライフサイエンス / 薬理学 /

経歴

2019年4月

-

現在

藤田医科大学医学部薬理学助教

学歴

2013年4月

-

2019年3月

藤田医科大学大学院医学研究科

2011年4月

-

2013年3月

藤田保健衛生大学大学院保健学研究科

2007年4月

-

2011年3月

藤田保健衛生大学医療科学部臨床検査学科

論文

Quinonoid dihydropteridine reductase, a tetrahydrobiopterin-recycling enzyme, contributes to 5-hydroxytryptamine-associated platelet aggregation in mice

Yui Suganuma Chiho Sumi-Ichinose Taiki Kano Kazuhisa Ikemoto Taei Matsui Hiroshi Ichinose Kazunao Kondo

Journal of Pharmacological Sciences 150 173-179 2022年6月 [査読有り]

Priapism caused by partial deficiency of tetrahydrobiopterin through hypofunction of the sympathetic neurons in sepiapterin reductase gene-disrupted mice

Chiho Sumi-Ichinose Yui Suganuma Taiki Kano Kazuhisa Ikemoto Noriko Ihira Hiroshi Ichinose Kazunao Kondo

Journal of Inherited Metabolic Disease 45(3) 621-634 2022年2月 [査読有り]

Salivary neopterin and related pterins: their comparison to those in plasma and changes in individuals

Kazuhisa Ikemoto Chiho Sumi-Ichinose Yui Suganuma Taiki Kano Noriko Ihira Toshiharu Nagatsu Kazunao Kondo

The Journal of Biochemistry 2021年6月

<title>Abstract</title>
Neopterin (NP), biopterin (BP) and monapterin (MP) exist in saliva. The physiological role of salivary NP as well as the pathophysiological role of increased NP in the immune-activated state has been unclear. Saliva is a c...

Effects of plasma glycosyltransferase on the ABO(H) blood group antigens of human von Willebrand factor

Taiki Kano Kazunao Kondo Jiharu Hamako Fumio Matsushita Kazuya Sakai Taei Matsui

International Journal of Hematology 108 1-6 2018年4月 [査読有り]

Von Willebrand factor (VWF) is one of the plasma protein carrying ABO(H) blood group antigens, but the combining process of these antigens is not clear. In the present study, we examined whether plasma glycosyltransferase affects the blood group a...

Sepiapterin reductase gene-disrupted mice suffer from hypertension with fluctuation and bradycardia

Chiho Sumi-Ichinose Yui Suganuma Taiki Kano Noriko Ihira Hiroko Nomura Kazuhisa Ikemoto Tadayoshi Hata Setsuko Katoh Hiroshi Ichinose Kazunao Kondo

Physiological Reports 5(6) e13196 2017年3月 [査読有り]

(6R)-l-erythro-5,6,7,8-Tetrahydrobiopterin (BH4) is an essential cofactor for monoamine and nitric oxide (NO) production. Sepiapterin reductase (SPR) catalyzes the final step in BH4 biosynthesis. We analyzed the cardiovascular function of adult Sp...