研究者氏名	三原圭一朗

URL
所属	藤田医科大学
部署	国際再生医療センター/先進がん免疫療法学
職名
学位	博士（医学）(広島大学)
科研費研究者番号	90363077
J-Global ID	201801010876392945

研究分野

ライフサイエンス / 血液、腫瘍内科学 /

学歴

1992年4月

1996年3月

広島大学医学系研究科内科系専攻

論文

12 3 4 5 >

Utility of cerebrospinal fluid liquid biopsy in distinguishing CNS lymphoma from cerebrospinal infectious/demyelinating diseases.

Chisako Iriyama Kenichiro Murate Sachiko Iba Akinao Okamoto Naoe Goto Hideyuki Yamamoto Toshiharu Kato Keichiro Mihara Takahiko Miyama Keiko Hattori Ryoko Kajiya Masataka Okamoto Yasuaki Mizutani Seiji Yamada Tetsuya Tsukamoto Yuichi Hirose Tatsuro Mutoh Hirohisa Watanabe Akihiro Tomita

Cancer medicine 12(16) 16972-16984 2023年8月

BACKGROUND: Distinguishing between central nervous system lymphoma (CNSL) and CNS infectious and/or demyelinating diseases, although clinically important, is sometimes difficult even using imaging strategies and conventional cerebrospinal fluid (C...

Acute fulminant intravascular hemolysis induced by Clostridium perfringens in a symptomatic multiple myeloma patient under immuno-chemotherapy.

Hideyuki Yamamoto Yuki Mizutani Chisako Iriyama Naoe Goto Akinao Okamoto Toshiharu Kato Chiyo Shintani Naoki Yamamoto Takahiko Miyama Keichiro Mihara Masataka Okamoto Akihiro Tomita

Annals of hematology 101(12) 2813-2815 2022年12月

NKp44-based chimeric antigen receptor effectively redirects primary T cells against synovial sarcoma.

Yudai Murayama Yasushi Kasahara Nobuhiro Kubo Chansu Shin Masaru Imamura Naoki Oike Takashi Ariizumi Akihiko Saitoh Minori Baba Tomohiro Miyazaki Yuko Suzuki Yiwei Ling Shujiro Okuda Keichiro Mihara Akira Ogose Hiroyuki Kawashima Chihaya Imai

Translational oncology 25 101521-101521 2022年11月

BACKGROUND: T-cell receptor-engineered T-cell therapies have achieved promising response rates against synovial sarcoma in clinical trials, but their applicability is limited owing to the HLA matching requirement. Chimeric antigen receptor (CAR) c...

Elevated METTL9 is associated with peritoneal dissemination in human scirrhous gastric cancers.

Toshifumi Hara Yuuki Tominaga Koji Ueda Keichiro Mihara Kazuyoshi Yanagihara Yoshifumi Takei

Biochemistry and biophysics reports 30 101255-101255 2022年7月

Methylation, the most common chemical modification of cellular components such as DNA, RNA, and proteins, impacts biological processes including transcription, RNA processing, and protein dynamics. Although abnormal expression of methyltransferase...

CD19-positive lymphocyte count is critical for acquisition of anti-SARS-CoV-2 IgG after vaccination in B-cell lymphoma.

Akinao Okamoto Hidetsugu Fujigaki Chisako Iriyama Naoe Goto Hideyuki Yamamoto Keichiro Mihara Yoko Inaguma Yasuo Miura Katsuya Furukawa Yukiya Yamamoto Yoshiki Akatsuka Senji Kasahara Kotaro Miyao Masutaka Tokuda Seiko Sato Yuki Mizutani Michiko Osawa Keiko Hattori Sachiko Iba Ryoko Kajiya Masataka Okamoto Kuniaki Saito Akihiro Tomita

Blood advances 6(11) 3230-3233 2022年6月