Yurika Ito   Mari Yamagata   Takuya Yamamoto   Katsuya Hirasaka   Takeshi Nikawa   Takahiko Sato   
eLife 12 2023年12月
Skeletal muscle atrophy and the inhibition of muscle regeneration are known to occur as a natural consequence of aging, yet the underlying mechanisms that lead to these processes in atrophic myofibers remain largely unclear. Our research has revea...
Aika Sawada   Takuya Yamamoto   Takahiko Sato   
International journal of molecular sciences 23(4) 2022年2月
The proliferation and differentiation of skeletal muscle cells are usually controlled by serum components. Myogenic differentiation is induced by a reduction of serum components in vitro. It has been recently reported that serum contains not only ...
<title>Abstract</title><sec>
<title>Background</title>
Mesenchymal stromal cells (MSCs) function as supportive cells on skeletal muscle homeostasis through several secretory factors including type 6 collagen (COL6). Several mutations of <italic>...
Journal of Neuromuscular Diseases 7(4) 395-405 2020年9月
Induced pluripotent stem cells (iPSCs) have the potential to differentiate into various types of cells and tissues including skeletal muscle. The approach to convert these stem cells into skeletal muscle cells offers hope for patients afflicted wi...