Bitiscetin-1 (aka bitiscetin) and bitiscetin-2 are C-type lectin-like proteins purified from the venom of Bitis arietans (puff adder). They bind to von Willebrand factor (VWF) and-at least bitiscetin-1-induce platelet agglutination via enhancement...
The Journal of general virology 102(4) 2021年4月 [査読有り]
With the recent establishment of robust reverse genetics systems for rotavirus, rotavirus is being developed as a vector to express foreign genes. However, insertion of larger sequences such as those encoding multiple foreign genes into the rotavi...
International Journal of Hematology 108(2) 1-6 2018年4月 [査読有り]
Von Willebrand factor (VWF) is one of the plasma protein carrying ABO(H) blood group antigens, but the combining process of these antigens is not clear. In the present study, we examined whether plasma glycosyltransferase affects the blood group a...
T. Matsui   A. Hori   J. Hamako   F. Matsushita   Y. Ozeki   Y. Sakurai   M. Hayakawa   M. Matsumoto   Y. Fujimura   
JOURNAL OF THROMBOSIS AND HAEMOSTASIS 15(3) 538-548 2017年3月 [査読有り]
Background Botrocetin-2 (Bot2) is a botrocetin-like protein composed of and subunits that have been cloned from the snake Bothrops jararaca. Bot2 binds specifically to von Willebrand factor (VWF), and the complex induces glycoprotein (GP) Ib-depen...