Kazuhiro J Fujimoto   Daniel C F Hobbs   Miki Umeda   Akihiro Nagata   Rie Yamaguchi   Yoshitaka Sato   Ayato Sato   Kohsuke Ohmatsu   Takashi Ooi   Takeshi Yanai   Hiroshi Kimura   Takayuki Murata   
Viruses 14(2) 2022年2月
Inhibition of transmembrane serine protease 2 (TMPRSS2) is expected to block the spike protein-mediated fusion of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Nafamostat, a potent TMPRSS2 inhibitor as well as a candidate for anti-...
Epstein-Barr virus (EBV) is an etiologic agent of infectious mononucleosis and several malignancies. Here, we found that reactivation of EBV resulted in increased programmed cell death-ligand 1 (PD-L1) expression in a cell type-dependent manner. L...
Infection, Genetics and Evolution : Journal of Molecular Epidemiology and Evolutionary Genetics in Infectious Diseases 96 105133-105133 2021年12月
Human rotavirus strains having the unconventional G4P[6] genotype have been sporadically identified in diarrheic patients in different parts of the world. However, the whole genome of only one human G4P[6] strain from Africa (central Africa) has b...
Epstein-Barr virus (EBV) is a causative agent of infectious mononucleosis and several types of cancer. Like other herpesviruses, it establishes an asymptomatic, life-long latent infection, with occasional reactivation and shedding of progeny virus...
Shouhei Miyagi   Takahiro Watanabe   Yuya Hara   Masataka Arata   Md Kamal Uddin   Keisuke Mantoku   Ken Sago   Yusuke Yanagi   Takeshi Suzuki   H M Abdullah Al Masud   Jun-Ichi Kawada   Shigeo Nakamura   Yasuyuki Miyake   Yoshitaka Sato   Takayuki Murata   Hiroshi Kimura   
Cancer science 2021年10月
Epstein-Barr virus-associated lymphoproliferative disease (EBV-LPD) is frequently fatal. Innate immunity plays a key role in protecting against pathogens and cancers. The stimulator of interferon genes (STING) is regarded as a key adaptor protein ...