Jyoji Morise Kenichi G N Suzuki Ayaka Kitagawa Yoshihiko Wakazono Kogo Takamiya Taka A Tsunoyama Yuri L Nemoto Hiromu Takematsu Akihiro Kusumi Shogo Oka
The number and subunit compositions of AMPA receptors (AMPARs), hetero- or homotetramers composed of four subunits GluA1-4, in the synapse is carefully tuned to sustain basic synaptic activity. This enables stimulation-induced synaptic plasticity,...
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 33(6) 7387-7402 2019年6月 [査読有り]
Glucocorticoids (GCs) potently induce T-cell apoptosis in a GC receptor (GR)-dependent manner and are used to control lymphocyte function in clinical practice. However, its downstream pathways remain controversial. Here, we showed that GC-induced ...
The human natural killer-1 (HNK-1) carbohydrate epitope, composed of a unique sulfated trisaccharide (HSO3-3GlcAβ1-3Galβ1-4GlcNAc-R), is highly expressed during brain development and regulates higher brain function. However, it remains unclear whi...
Naoko Matsubara Akihiro Imamura Tatsuya Yonemizu Chizuru Akatsu Hongrui Yang Akiharu Ueki Natsuki Watanabe Hajjaj Abdu-Allah Nobutaka Numoto Hiromu Takematsu Shinobu Kitazume Thomas F. Tedder Jamey D. Marth Nobutoshi Ito Hiromune Ando Hideharu Ishida Makoto Kiso Takeshi Tsubata
Frontiers in Immunology 9 820 2018年4月 [査読有り]
Sialic acid-binding immunoglobulin-like lectins (Siglecs) are expressed in various immune cells and most of them carry signaling functions. High-affinity synthetic sialoside ligands have been developed for various Siglecs. Therapeutic potentials o...
Cellular translation should be precisely controlled in response to extracellular cues. However, knowledge is limited concerning signal transduction-regulated translation. In the present study, phosphorylation was identified in the 40S small subuni...
Cindy M. Spruit Nikoloz Nemanichvili Masatoshi Okamatsu Hiromu Takematsu Geert-Jan Boons Robert P. de Vries
Viruses 13(5) 815-815 2021年5月 [査読有り]
The first step in influenza virus infection is the binding of hemagglutinin to sialic acid-containing glycans present on the cell surface. Over 50 different sialic acid modifications are known, of which N-acetylneuraminic acid (Neu5Ac) and N-glyco...
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