衛生学 - 藤田医科大学教育・研究業績

研究分野

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ライフサイエンス / 栄養学、健康科学 /
ライフサイエンス / 衛生学、公衆衛生学分野：実験系を含まない /
ライフサイエンス / 衛生学、公衆衛生学分野：実験系を含む /
ライフサイエンス / 医療管理学、医療系社会学 /
ライフサイエンス / 代謝、内分泌学 /

受賞

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2010年

大阪大学大学院医学系研究科保健学専攻優秀論文賞
山田宏哉

日本臨床検査医学会, 若手研究奨励賞
山田宏哉

第56日本甲状腺学会コスミック・研究創成賞優秀賞
山田宏哉

予防医学研究海外研修奨学助成金：甕哲司賞
山田宏哉

第53回日本甲状腺学会若手奨励賞
山田宏哉

論文

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Association between serum carotenoids and premature mortality in a population-based case-control study.

Ryosuke Fujii Koji Suzuki Hiroya Yamada Miyuki Kawado Shuji Hashimoto Yoshiki Tsuboi Kenji Wakai Hiroyasu Iso Yoshiyuki Watanabe Yoshihisa Fujino Akiko Tamakoshi

Nagoya journal of medical science 84(3) 607-620 2022年8月

Carotenoids are abundant pigments mainly contained in vegetables and fruits, and show antioxidant properties by quenching free radicals in human body. Few studies have investigated associations between serum carotenoid levels and premature mortali...

High-fructose corn syrup intake has stronger effects on the transcription level of hepatic lipid metabolism-related genes, via DNA methylation modification, in childhood and adolescence than in other generations.

Genki Mizuno Hiroya Yamada Eiji Munetsuna Yoshitaka Ando Atsushi Teshigawara Manaka Ito Itsuki Kageyama Yuki Nouchi Takuya Wakasugi Tomohide Sakakibara Mirai Yamazaki Ryosuke Fujii Hiroaki Ishikawa Koji Suzuki Shuji Hashimoto Koji Ohashi

Life sciences 301 120638-120638 2022年5月

AIMS: This study aimed to analyze differences in sensitivity to hepatic lipid metabolism at different ages, through DNA methylation, using an experimental rat model of high-fructose corn syrup (HFCS) intake. MAIN METHODS: The experimental was divi...

Maternal high-fructose corn syrup consumption causes insulin resistance and hyperlipidemia in offspring via DNA methylation of the Pparα promoter region.

Yoshitaka Ando Hiroya Yamada Eiji Munetsuna Mirai Yamazaki Itsuki Kageyama Atsushi Teshigawara Yuki Nouchi Ryosuke Fujii Genki Mizuno Nao Sadamoto Hiroaki Ishikawa Koji Suzuki Shuji Hashimoto Koji Ohashi

The Journal of nutritional biochemistry 103 108951-108951 2022年5月

There are concerns about the negative effects of fructose intake during pregnancy on the next generation. We have previously reported that offspring from dams fed with fructose during gestation and lactation demonstrate abnormal lipid metabolism i...

Circulating microRNA-27a and -133a are negatively associated with incident hypertension: A five-year longitudinal population-based study.

Koji Suzuki Hiroya Yamada Ryosuke Fujii Eiji Munetsuna Mirai Yamazaki Yoshitaka Ando Koji Ohashi Hiroaki Ishikawa Genki Mizuno Yohiski Tsuboi Shuji Hashimoto Nobuyuki Hamajima

Biomarkers : biochemical indicators of exposure, response, and susceptibility to chemicals 27(5) 1-16 2022年4月

BACKGROUND Previous cross-sectional studies have shown that several circulating microRNA levels are associated with hypertension, but there are no prospective studies among general populations.OBJECTIVE We evaluated the impact of circulating infla...

Increased risk of cancer mortality by smoking-induced aryl hydrocarbon receptor repressor DNA hypomethylation in Japanese population: A long-term cohort study.

Yoshiki Tsuboi Hiroya Yamada Eiji Munetsuna Ryosuke Fujii Mirai Yamazaki Yoshitaka Ando Genki Mizuno Yuji Hattori Hiroaki Ishikawa Koji Ohashi Shuji Hashimoto Nobuyuki Hamajima Koji Suzuki

Cancer epidemiology 78 102162-102162 2022年4月

BACKGROUND: Smoking is well known to be a major risk factor for cancer, and to decrease the levels of aryl hydrocarbon receptor repressor (AHRR) DNA methylation. AHRR is a key regulator for AHR signaling, which is involved in chemical metabolism a...