BRIEF BIOGRAPHY: While Prof. Dr. Yukio Ozaki is an interventional cardiologist having specialty in the field of acute myocardial infarction (Ozaki Y. et al; CVIT expert consensus document on primary PCI for AMI in 2018. Cardiovasc Interv Ther. 2018;33:178-203), coronary imaging such as OCT, IVUS, NIRS, angioscopy, CT angiography as well as structural heart disease (SHD). While Dr. Yukio Ozaki is the first Japanese fellow under the supervision of Prof. Patrick W. Serruys in the Thoraxcenter Erasmus University Rotterdam, he defended his thesis entitled “Clinical Application of IVUS and QCA to Assess PCI and Atherosclerosis” at Erasmus University Rotterdam. Based on his Rotterdam experience, Prof. Dr. Yukio Ozaki proposed for the first time that intact fibrous cap ACS (IFC-ACS) by OCT and angioscopy would be plaque erosion (EHJ 2011), reported firstly integrated backscatter IVUS defined thin cap fibroatheroma (TCFA) in comparison with OCT (Circ J 2015), initially examine the fate of incomplete stent apposition (ISA) in DES by OCT (EHJ 2010). While Yukio Ozaki, Sadako Motoyama and Jagat Narula initially reported that positive remodeling (PR) and low attenuation plaque (LAP) are crucial factors in ACS lesions by CT angiography, they published these features could predict the occurrence of future ACS and play a role in the long-term prognosis for the first time (JACC 2007, JACC 2009 & JACC 2015). Subsequently, Dr. Ozaki’s CITATION INDEX has reached 7,214 by Pure System in Elsevier in December 2019.
Heart and vessels 34(12) 1899-1908 2019年12月 [査読有り]
It is known that incidence and short-term mortality rate of acute myocardial infarction (AMI) tend to be higher in the cold season. The aim of our study was to investigate the association of onset-season with patient characteristics and long-term ...
Cardiovascular intervention and therapeutics 34(4) 297-304 2019年10月 [査読有り]
This study evaluated whether radial access intervention had a lower risk of post-treatment adverse events in acute coronary syndrome (ACS) even in Japan where the use of a strong antithrombotic regimen was not approved. We retrospectively analyzed...
International journal of hematology 110(3) 285-294 2019年9月 [査読有り]
Soluble forms of platelet membrane proteins are released upon platelet activation. We previously reported that soluble C-type lectin-like receptor 2 (sCLEC-2) is released as a shed fragment (Shed CLEC-2) or as a whole molecule associated with plat...
Kawai H   Ohta M   Motoyama S   Hashimoto Y   Takahashi H   Muramatsu T   Sarai M   Narula J   Ozaki Y   
Prati F   Romagnoli E   Gatto L   La Manna A   Burzotta F   Ozaki Y   Marco V   Boi A   Fineschi M   Fabbiocchi F   Taglieri N   Niccoli G   Trani C   Versaci F   Calligaris G   Ruscica G   Di Giorgio A   Vergallo R   Albertucci M   Biondi-Zoccai G   Tamburino C   Crea F   Alfonso F   Arbustini E   CLIMA Investigators   
International journal of cardiology. Heart & vasculature 22 111-116 2019年3月
Background: Since warfarin is primarily bound to serum albumin, hypoalbuminemia is likely to increase the free fraction of warfarin and to increase the risk of bleeding. We prospectively evaluated the impact of serum albumin levels (ALB) on intern...
We have previously demonstrated that cardiac shock wave therapy (CSWT) effectively improves myocardial ischemia through coronary neovascularization both in a porcine model of chronic myocardial ischemia and in patients with refractory angina pecto...
BACKGROUND: Although cardiac sarcoidosis is associated with poor prognosis, diagnosis of the disease is challenging and the sensitivity and specificity of diagnostic modalities are limited. This study was performed to evaluate the potential of ser...
Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association 27(11) 3148-3154 2018年11月
BACKGROUND: Cardiac wall motion abnormality (WMA) is a common complication in patients with subarachnoid hemorrhage (SAH) and is one determinant of their prognosis. The aim of this study was to examine whether the electrocardiography (ECG) finding...
Circulation journal : official journal of the Japanese Circulation Society 82(11) 2715-2721 2018年10月
BACKGROUND: In atrial fibrillation (AF) patients, the effect of direct oral anticoagulant (DOACs) therapy on the incidence of left atrial appendage thrombus (LAT) remains poorly investigated. This study examined the prevalence and risk factors of ...
Ito H   Motoyama S   Sarai M   Kawai H   Nagahara Y   Harigaya H   Kan S   Naruse H   Ishii J   Ozaki Y   
Shiino K   Sugimoto K   Yamada A   Inuzuka H   Kato M   Sone M   Takada K   Sugimoto K   Takagi Y   Iwase M   Ozaki Y   
Naruse H   Ishii J   Okuyama R   Ohta M   Hashimoto T   Hattori K   Okumura M   Mori Y   Matsui S   Izawa H   Ozaki Y   
Ito H   Motoyama S   Sarai M   Kawai H   Nagahara Y   Takada K   Okumura M   Naruse H   Ishii J   Ozaki Y