BRIEF BIOGRAPHY: While Prof. Dr. Yukio Ozaki is an interventional cardiologist having specialty in the field of acute myocardial infarction (Ozaki Y. et al; CVIT expert consensus document on primary PCI for AMI in 2018. Cardiovasc Interv Ther. 2018;33:178-203), coronary imaging such as OCT, IVUS, NIRS, angioscopy, CT angiography as well as structural heart disease (SHD). While Dr. Yukio Ozaki is the first Japanese fellow under the supervision of Prof. Patrick W. Serruys in the Thoraxcenter Erasmus University Rotterdam, he defended his thesis entitled “Clinical Application of IVUS and QCA to Assess PCI and Atherosclerosis” at Erasmus University Rotterdam. Based on his Rotterdam experience, Prof. Dr. Yukio Ozaki proposed for the first time that intact fibrous cap ACS (IFC-ACS) by OCT and angioscopy would be plaque erosion (EHJ 2011), reported firstly integrated backscatter IVUS defined thin cap fibroatheroma (TCFA) in comparison with OCT (Circ J 2015), initially examine the fate of incomplete stent apposition (ISA) in DES by OCT (EHJ 2010). While Yukio Ozaki, Sadako Motoyama and Jagat Narula initially reported that positive remodeling (PR) and low attenuation plaque (LAP) are crucial factors in ACS lesions by CT angiography, they published these features could predict the occurrence of future ACS and play a role in the long-term prognosis for the first time (JACC 2007, JACC 2009 & JACC 2015). Subsequently, Dr. Ozaki’s CITATION INDEX has reached 7,214 by Pure System in Elsevier in December 2019.
Heart and vessels 34(12) 1899-1908 2019年12月 [査読有り]
It is known that incidence and short-term mortality rate of acute myocardial infarction (AMI) tend to be higher in the cold season. The aim of our study was to investigate the association of onset-season with patient characteristics and long-term ...
Cardiovascular intervention and therapeutics 34(4) 297-304 2019年10月 [査読有り]
This study evaluated whether radial access intervention had a lower risk of post-treatment adverse events in acute coronary syndrome (ACS) even in Japan where the use of a strong antithrombotic regimen was not approved. We retrospectively analyzed...
International journal of hematology 110(3) 285-294 2019年9月 [査読有り]
Soluble forms of platelet membrane proteins are released upon platelet activation. We previously reported that soluble C-type lectin-like receptor 2 (sCLEC-2) is released as a shed fragment (Shed CLEC-2) or as a whole molecule associated with plat...
Prati F Romagnoli E Gatto L La Manna A Burzotta F Ozaki Y Marco V Boi A Fineschi M Fabbiocchi F Taglieri N Niccoli G Trani C Versaci F Calligaris G Ruscica G Di Giorgio A Vergallo R Albertucci M Biondi-Zoccai G Tamburino C Crea F Alfonso F Arbustini E CLIMA Investigators
Journal of the American Heart Association 7(11) 2018年5月
BACKGROUND: Prediction of thrombotic and bleeding risk is important to optimize antithrombotic therapy after percutaneous coronary intervention. METHODS AND RESULTS: We developed the prediction rules for thrombotic and bleeding events separately i...
BACKGROUND: Current guidelines call for high-intensity statin therapy in patients with cardiovascular disease on the basis of several previous "more versus less statins" trials. However, no clear evidence for more versus less statins has been esta...
The ratio of serum eicosapentaenoic acid (EPA) to arachidonic acid (AA) is significantly associated with long-term clinical outcomes in patients with acute myocardial infarction (AMI). However, it has not been conclusively demonstrated that higher...
Yoshihiro Sobue Eiichi Watanabe Gregory Y H Lip Masayuki Koshikawa Tomohide Ichikawa Mayumi Kawai Masahide Harada Joji Inamasu Yukio Ozaki
Heart and vessels 33(4) 403-412 2018年4月
Heart failure (HF) is classified into three clinical subtypes: HF with a preserved ejection fraction (HFpEF: EF ≥ 50%), HF with a mid-range ejection fraction (HFmrEF: 40 ≤ EF < 49%), and HF with a reduced ejection fraction (HFrEF: EF < 40%). These...
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