研究者氏名	井手富彦

URL
所属	藤田医科大学
部署	研究支援推進本部共同利用研究設備サポートセンター
職名	助教
学位	学位(医学)
J-Global ID	201501006572142323

研究分野

ライフサイエンス / ウイルス学 /

論文

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Genomic analysis of group A rotavirus G12P[8] including a new Japanese strain revealed evidence for intergenotypic recombination in VP7 and VP4 genes.

Tung Phan Tomihiko Ide Satoshi Komoto Pattara Khamrin Ngan Thi Kim Pham Shoko Okitsu Koki Taniguchi Shuichi Nishimura Niwat Maneekarn Satoshi Hayakawa Hiroshi Ushijima

Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases 87 104656-104656 2021年1月

Group A rotavirus is a leading cause of severe acute gastroenteritis worldwide. In this study, the first complete coding sequences of 11 RNA segments of human group A rotavirus G12P[8] in Japan were determined by an unbiased viral metagenomics. It...

Genomic characterization of a novel G3P[10] rotavirus strain from a diarrheic child in Thailand: Evidence for bat-to-human zoonotic transmission.

Satoshi Komoto Ratana Tacharoenmuang Ratigorn Guntapong Sompong Upachai Phakapun Singchai Tomihiko Ide Saori Fukuda Riona Hatazawa Karun Sutthiwarakom Santip Kongjorn Napa Onvimala Tipsuda Luechakham Busarawan Sriwanthana Takayuki Murata Ballang Uppapong Koki Taniguchi

Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases 87 104667-104667 2021年1月

An unusual rotavirus strain with the G3P[10] genotype (RVA/Human-wt/THA/MS2015-1-0001/2015/G3P[10]) was identified in a stool sample from a hospitalized child aged 11 months with severe gastroenteritis in Thailand. In the current study, we sequenc...

Unusual mono-reassortant of a Wa-like G1P[8] species A rotavirus containing a DS-1-like (genotype 2) NSP4 gene.

Tung Phan Tomihiko Ide Satoshi Komoto Pattara Khamrin Shoko Okitsu Koki Taniguchi Hideaki Kikuta Niwat Maneekarn Satoshi Hayakawa Hiroshi Ushijima

Virus genes 56(5) 638-641 2020年10月 [査読有り]

Species A rotaviruses are a major cause of acute gastroenteritis in infants and young children worldwide. Reassortment is a common phenomenon due to the segmented nature of the rotavirus genome. The complete coding sequences of a species A rotavir...

Molecular characterization of rotaviruses obtained from patients with rotavirus-associated encephalitis/encephalopathy.

Masaru Ihira Yoshiki Kawamura Hiroki Miura Fumihiko Hattori Yuki Higashimoto Ken Sugata Tomihiko Ide Satoshi Komoto Koki Taniguchi Tetsushi Yoshikawa

Microbiology and immunology 64(8) 541-555 2020年8月 [査読有り]

Group A rotavirus (RVA) rarely causes severe complications such as encephalitis/encephalopathy. However, the pathophysiology of this specific complication remains unclear. Next-generation sequence analysis was used to compare the entire genome seq...

High prevalence of equine-like G3P[8] rotavirus in children and adults with acute gastroenteritis in Thailand.

Ratana Tacharoenmuang Satoshi Komoto Ratigorn Guntapong Sompong Upachai Phakapun Singchai Tomihiko Ide Saori Fukuda Kriangsak Ruchusatsawast Busarawan Sriwantana Masashi Tatsumi Kazushi Motomura Naokazu Takeda Takayuki Murata Somchai Sangkitporn Koki Taniguchi Tetsushi Yoshikawa

Journal of medical virology 92(2) 174-186 2020年2月 [査読有り]

Group A rotavirus (RVA) is a major cause of acute gastroenteritis in infants and young children worldwide. This study aims to clarify the distribution of G/P types and genetic characteristics of RVAs circulating in Thailand. Between January 2014 a...

MISC

Modification of the trypsin cleavage site of rotavirus VP4 to a furin-sensitive form does not enhance replication efficiency.

Satoshi Komoto Mitsutaka Wakuda Tomihiko Ide Gen Niimi Yoshimasa Maeno Kyoko Higo-Moriguchi Koki Taniguchi

The Journal of general virology 92(Pt 12) 2914-2921 2011年12月 [査読有り]

The infectivity of rotavirus (RV) is dependent on an activation process triggered by the proteolytic cleavage of its spike protein VP4. This activation cleavage is performed by exogenous trypsin in the lumen of the intestines in vivo. Here, we rep...

Porcine rotavirus closely related to novel group of human rotaviruses.

Mitsutaka Wakuda Tomihiko Ide Jun Sasaki Satoshi Komoto Junichi Ishii Takeshi Sanekata Koki Taniguchi

Emerging infectious diseases 17(8) 1491-3 2011年8月 [査読有り]

We determined nucleotide sequences and inferred amino acid sequences of viral protein (VP) 4, VP6, VP7, and nonstructural protein 4 genes of a porcine rotavirus strain (SKA-1) from Japan. The strain was closely related to a novel group of human ro...

三重県で流行しているヒトロタウイルスの外層タンパク質ＶＰ７コード遺伝子の性状

神谷元油井晶子井手富彦谷口孝喜

藤田学園医学会誌 35(1) 65-69 2011年

Budding and direct division of adult human erythrocytes in serum-free cultures.

Gen Niimi Koji Ohashi Tomihiko Ide Jaime Pereda

Okajimas folia anatomica Japonica 86(3) 73-7 2009年11月 [査読有り]

This paper documents the budding and division process of human erythrocytes in vitro using time-lapse light microscopy of hanging-drop preparations. The erythrocytes were prepared from normal adult human peripheral blood. Red blood cells showed cy...