研究者氏名	井手富彦

URL
所属	藤田医科大学
部署	研究支援推進本部共同利用研究設備サポートセンター
職名	助教
学位	学位(医学)
J-Global ID	201501006572142323

研究分野

ライフサイエンス / ウイルス学 /

論文

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Characterization of a G10P[14] rotavirus strain from a diarrheic child in Thailand: Evidence for bovine-to-human zoonotic transmission.

Ratana Tacharoenmuang Satoshi Komoto Ratigorn Guntapong Tomihiko Ide Phakapun Singchai Sompong Upachai Saori Fukuda Yumika Yoshida Takayuki Murata Tetsushi Yoshikawa Kriangsak Ruchusatsawat Kazushi Motomura Naokazu Takeda Somchai Sangkitporn Koki Taniguchi

Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases 63 43-57 2018年9月 [査読有り]

An unusual rotavirus strain, DB2015-066 with the G10P[14] genotype (RVA/Human-wt/THA/DB2015-066/2015/G10P[14]), was detected in a stool sample from a child hospitalized with acute gastroenteritis in Thailand. Here, we sequenced and characterized t...

Generation of Recombinant Rotaviruses Expressing Fluorescent Proteins by Using an Optimized Reverse Genetics System.

Satoshi Komoto Saori Fukuda Tomihiko Ide Naoto Ito Makoto Sugiyama Tetsushi Yoshikawa Takayuki Murata Koki Taniguchi

Journal of virology 92(13) 2018年7月 [査読有り]

An entirely plasmid-based reverse genetics system for rotaviruses was established very recently. We improved the reverse genetics system to generate recombinant rotavirus by transfecting only 11 cDNA plasmids for its 11 gene segments under the con...

Characterization of unusual DS-1-like G3P[8] rotavirus strains in children with diarrhea in Japan.

Satoshi Komoto Tomihiko Ide Manami Negoro Takaaki Tanaka Kazutoyo Asada Masakazu Umemoto Haruo Kuroki Hiroaki Ito Shigeki Tanaka Mitsue Ito Saori Fukuda Shigeru Suga Hajime Kamiya Takashi Nakano Koki Taniguchi

Journal of medical virology 90(5) 890-898 2018年5月 [査読有り]

The emergence and rapid spread of novel DS-1-like intergenogroup reassortant rotaviruses having the equine-like G3 genotype (DS-1-like G3P[8] strains) have been recently reported from several countries. During rotavirus surveillance in Japan in 20...

Molecular epidemiology of rotavirus gastroenteritis in Central Kenya before vaccine introduction, 2009-2014.

Ernest A Wandera Shah Mohammad Satoshi Komoto Yoshimasa Maeno James Nyangao Tomihiko Ide Cyrus Kathiiko Erick Odoyo Takao Tsuji Koki Taniguchi Yoshio Ichinose

Journal of medical virology 89(5) 809-817 2017年5月 [査読有り]

Between July 2009 and June 2014, a total of 1,546 fecal specimens were collected from children <5 years of age with acute gastroenteritis admitted to Kiambu County Hospital, Central Kenya. The specimens were screened for group A rotavirus (RVA) us...

Identification and characterization of a human G9P[23] rotavirus strain from a child with diarrhoea in Thailand: evidence for porcine-to-human interspecies transmission.

Satoshi Komoto Ratana Tacharoenmuang Ratigorn Guntapong Tomihiko Ide Phakapun Sinchai Sompong Upachai Saori Fukuda Tetsushi Yoshikawa Piyanit Tharmaphornpilas Somchai Sangkitporn Koki Taniguchi

The Journal of general virology 98(4) 532-538 2017年4月 [査読有り]

An unusual rotavirus strain with the G9P[23] genotype (RVA/Human-wt/THA/KKL-117/2014/G9P[23]) was identified in a stool specimen from a 10-month-old child hospitalized with severe diarrhoea. In this study, we sequenced and characterized the comple...

MISC

Modification of the trypsin cleavage site of rotavirus VP4 to a furin-sensitive form does not enhance replication efficiency.

Satoshi Komoto Mitsutaka Wakuda Tomihiko Ide Gen Niimi Yoshimasa Maeno Kyoko Higo-Moriguchi Koki Taniguchi

The Journal of general virology 92(Pt 12) 2914-2921 2011年12月 [査読有り]

The infectivity of rotavirus (RV) is dependent on an activation process triggered by the proteolytic cleavage of its spike protein VP4. This activation cleavage is performed by exogenous trypsin in the lumen of the intestines in vivo. Here, we rep...

Porcine rotavirus closely related to novel group of human rotaviruses.

Mitsutaka Wakuda Tomihiko Ide Jun Sasaki Satoshi Komoto Junichi Ishii Takeshi Sanekata Koki Taniguchi

Emerging infectious diseases 17(8) 1491-3 2011年8月 [査読有り]

We determined nucleotide sequences and inferred amino acid sequences of viral protein (VP) 4, VP6, VP7, and nonstructural protein 4 genes of a porcine rotavirus strain (SKA-1) from Japan. The strain was closely related to a novel group of human ro...

三重県で流行しているヒトロタウイルスの外層タンパク質ＶＰ７コード遺伝子の性状

神谷元油井晶子井手富彦谷口孝喜

藤田学園医学会誌 35(1) 65-69 2011年

Budding and direct division of adult human erythrocytes in serum-free cultures.

Gen Niimi Koji Ohashi Tomihiko Ide Jaime Pereda

Okajimas folia anatomica Japonica 86(3) 73-7 2009年11月 [査読有り]

This paper documents the budding and division process of human erythrocytes in vitro using time-lapse light microscopy of hanging-drop preparations. The erythrocytes were prepared from normal adult human peripheral blood. Red blood cells showed cy...