生理学Ⅰ - 藤田医科大学教育・研究業績

研究キーワード

幹細胞 ,下垂体 ,視床下部 ,神経内分泌学

研究分野

ライフサイエンス / 神経科学一般 /
ライフサイエンス / 生理学 /

経歴

2020年4月

-

現在

藤田医科大学医学部生理学I 講師

2018年10月

-

2020年3月

藤田医科大学医学部生理学I 助教

2012年5月

-

2018年9月

藤田保健衛生大学医学部生理学I 助教

2012年4月

広島大学大学院総合科学研究科研究員

学歴

2007年4月

-

2012年3月

広島大学大学院総合科学研究科

受賞

2019年10月

日本神経内分泌学会, 第19回若手研究奨励賞
小谷侑

論文

12 3 4 >

EpCAM Is a Surface Marker for Enriching Anterior Pituitary Cells From Human Hypothalamic-Pituitary Organoids

Yu Kodani Miho Kawata Hidetaka Suga Takatoshi Kasai Chikafumi Ozone Mayu Sakakibara Atsushi Kuwahara Shiori Taga Hiroshi Arima Toshiki Kameyama Kanako Saito Akira Nakashima Hiroshi Nagasaki

Frontiers in Endocrinology 13 941166 2022年7月 [査読有り]

Human stem cell-derived organoid culture enables the in vitro analysis of the cellular function in three-dimensional aggregates mimicking native organs, and also provides a valuable source of specific cell types in the human body. We previously es...

Characterization of Hypothalamic MCH Neuron Development in a 3D Differentiation System of Mouse Embryonic Stem Cells

Yu Kodani Miho Kawata Hidetaka Suga Yoko S. Kaneko Akira Nakashima Toshiki Kameyama Kanako Saito Hiroshi Nagasaki

eNeuro 9(2) ENEURO.0442-21.2022 2022年4月 [査読有り]

NT5DC2 affects the phosphorylation of tyrosine hydroxylase regulating its catalytic activity.

Akira Nakashima Hisateru Yamaguchi Mii Kondo Takahiro Furumura Yu Kodani Yoko S Kaneko Miho Kawata Hiroshi Nagasaki Toshiharu Nagatsu Akira Ota

Journal of Neural Transmission (Vienna, Austria : 1996) 127(12) 1631-1640 2020年8月 [査読有り]

5'-Nucleotidase domain-containing protein 2 (NT5DC2) has been revealed by genome-wide association studies (GWAS) as a gene implicated in neuropsychiatric disorders related to the abnormality of dopamine (DA) activity in the brain. Based on its ami...

Hypothalamic Contribution to Pituitary Functions Is Recapitulated In Vitro Using 3D-Cultured Human iPS Cells.

Takatoshi Kasai Hidetaka Suga Mayu Sakakibara Chikafumi Ozone Ryusaku Matsumoto Mayuko Kano Kazuki Mitsumoto Koichiro Ogawa Yu Kodani Hiroshi Nagasaki Naoko Inoshita Mariko Sugiyama Takeshi Onoue Taku Tsunekawa Yoshihiro Ito Hiroshi Takagi Daisuke Hagiwara Shintaro Iwama Motomitsu Goto Ryoichi Banno Jun Takahashi Hiroshi Arima

Cell Reports 30(1) 18-24 2020年1月 [査読有り]

The pituitary is a major hormone center that secretes systemic hormones responding to hypothalamus-derived-releasing hormones. Previously, we reported the independent pituitary induction and hypothalamic differentiation of human embryonic stem cel...

Identification by nano-LC-MS/MS of NT5DC2 as a protein binding to tyrosine hydroxylase: Down-regulation of NT5DC2 by siRNA increases catecholamine synthesis in PC12D cells

Nakashima A Yamaguchi H Kodani Y Kaneko YS Kawata M Nagasaki H Nagatsu T Ota A

Biochem Biophys Res Commun 516(4) 1060-1065 2019年 [査読有り]