Koki Nagaoka   Takuya Nagashima   Nozomi Asaoka   Hiroki Yamamoto   Chihiro Toda   Gen Kayanuma   Soni Siswanto   Yasuhiro Funahashi   Keisuke Kuroda   Kozo Kaibuchi   Yasuo Mori   Kazuki Nagayasu   Hisashi Shirakawa   Shuji Kaneko   
JCI insight 6(10) 2021年5月
Antipsychotics often cause tardive dyskinesia, an adverse symptom of involuntary hyperkinetic movements. Analysis of the US Food and Drug Administration Adverse Event Reporting System and JMDC insurance claims revealed that acetaminophen prevented...
Current opinion in cell biology 63 76-87 2020年2月 [査読有り]
Neurons are highly polarized cells that have structurally and functionally distinct processes called axons and dendrites. How neurons establish polarity is one of the fundamental questions of neuroscience. In the last decade, significant progress ...
Dopamine (DA) activates mitogen-activated protein kinase (MAPK) via protein kinase A (PKA)/Rap1 in medium spiny neurons (MSNs) expressing the dopamine D1 receptor (D1R) in the nucleus accumbens (NAc), thereby regulating reward-related behavior. Ho...
Nishino T   Tamada K   Maeda A   Abe T   Kiyonari H   Funahashi Y   Kaibuchi K   Takumi T   Konishi H   
Journal of biochemistry 165(4) 301-307 2019年4月 [査読有り]
Accumulating information on eukaryotic protein phosphorylation implies a large and complicated phospho-signalling network in various cellular processes. Although a large number of protein phosphorylation sites have been detected, their physiologic...