Hideo Hagihara Tomoyasu Horikawa Yasuhiro Irino Hironori K Nakamura Juzoh Umemori Hirotaka Shoji Masaru Yoshida Yukiyasu Kamitani Tsuyoshi Miyakawa
Molecular Brain 12(1) 107 2019年12月 [査読有り]
Bipolar disorder is a major mental illness characterized by severe swings in mood and activity levels which occur with variable amplitude and frequency. Attempts have been made to identify mood states and biological features associated with mood c...
It is agreed upon that adult hippocampal neurogenesis (AHN) occurs in the dentate gyrus (DG) in rodents. However, the existence of AHN in humans, particularly in elderly individuals, remains to be determined. Recently, several studies reported tha...
Koji Ohira Hideo Hagihara Miki Miwa Katsuki Nakamura Tsuyoshi Miyakawa
Molecular Brain 12(1) 69 2019年8月 [査読有り]
The selective serotonin reuptake inhibitor fluoxetine (FLX) is widely used to treat depression and anxiety disorders. Chronic FLX treatment reportedly induces cellular responses in the brain, including increased adult hippocampal and cortical neur...
（Nakajima et al. Similarities of developmental gene expression changes in the brain between human and experimental animals: rhesus monkey, mouse, Zebrafish, and Drosophila. Molecular Brain. 2021.14(1):135;
Hagihara et al. Transcriptomic evidence for immaturity induced by antidepressant fluoxetine in the hippocampus and prefrontal cortex. Neuropsychopharmacology Reports. 2019. 39(2):78-89;
Murano et al. Transcriptomic immaturity inducible by neural hyperexcitation is shared by multiple neuropsychiatric disorders. Communications Biology. 2019. 2:32;
Hagihara et al. Transcriptomic evidence for immaturity of the prefrontal cortex in patients with schizophrenia. Molecular Brain. 2014. 7:41）
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