Although the brains of patients with schizophrenia and bipolar disorder exhibit decreased brain pH relative to those of healthy controls upon postmortem examination, it remains controversial whether this finding reflects a primary feature of the d...
Accumulating evidence suggests that subcellular-scale structures such as dendritic spine and mitochondria may be involved in the pathogenesis/pathophysiology of schizophrenia and intellectual disability. Previously, we proposed mice lacking Schnur...
(Nakajima et al. Similarities of developmental gene expression changes in the brain between human and experimental animals: rhesus monkey, mouse, Zebrafish, and Drosophila. Molecular Brain. 2021.14(1):135;
Hagihara et al. Transcriptomic evidence for immaturity induced by antidepressant fluoxetine in the hippocampus and prefrontal cortex. Neuropsychopharmacology Reports. 2019. 39(2):78-89;
Murano et al. Transcriptomic immaturity inducible by neural hyperexcitation is shared by multiple neuropsychiatric disorders. Communications Biology. 2019. 2:32;
Hagihara et al. Transcriptomic evidence for immaturity of the prefrontal cortex in patients with schizophrenia. Molecular Brain. 2014. 7:41)