Kanako Saito Veronique Dubreuil Yoko Arai Michaela Wilsch-Bräuninger Dominik Schwudke Gesine Saher Takaki Miyata Georg Breier Christoph Thiele Andrej Shevchenko Klaus-Armin Nave Wieland B Huttner
Proceedings of the National Academy of Sciences of the United States of America 106(20) 8350-5 2009年5月 [査読有り]
Although sufficient cholesterol supply is known to be crucial for neurons in the developing mammalian brain, the cholesterol requirement of neural stem and progenitor cells in the embryonic central nervous system has not been addressed. Here we ha...
Developmental dynamics : an official publication of the American Association of Anatomists 236(11) 3061-70 2007年11月 [査読有り]
To understand the morphogenetic dynamics of the inner surface of the embryonic pallial (neocortical) wall, we immunohistochemically surveyed the cellular endfeet facing the lateral ventricle and found that the average endfoot area was minimal at e...
Genes to cells : devoted to molecular & cellular mechanisms 12(9) 983-96 2007年9月 [査読有り]
The mammalian cerebral cortex develops from proliferative neuroepithelial cells that exhibit a cell cycle-dependent nuclear movement (interkinetic nuclear migration; INM). Pax6 transcription factor plays pivotal roles in various aspects of cortico...
Nagoya journal of medical science 67(3-4) 65-70 2005年6月 [査読有り]
For the understanding of histogenetic events in the three-dimensional brain primordia, direct observation of progenitor cells and young neurons is required. Although slice culture, which is one of the tissue or organ culture methods, effectively p...
Journal of neuroscience research 78(6) 784-95 2004年12月 [査読有り]
Progenitor cells that generate neuron pairs ("pair progenitor cells") are implicated in mammalian cortical development, and their division has been thought to be "symmetric." However, asymmetric growth of two sister neurons generated by the divisi...
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