Epithelial-mesenchymal interactions are very important in the development of the vertebrate gut. In the avian embryonic stomach (proventriculus), expression of embryonic chick pepsinogen (ECPg) gene, which is specific to developing glandular cells...
A micromass culture (MM-C) system of primary immature chondrocytes for functional analysis of soluble factors involved in the maturation step of cartilage was previously developed. Ectopically expressed BMP-2 was shown to induce the expression of ...
A Sukegawa   T Narita   T Kameda   K Saitoh   T Nohno   H Iba   S Yasugi   K Fukuda   
Development (Cambridge, England) 127(9) 1971-80 2000年5月 [査読有り]
The embryonic gut of vertebrates consists of endodermal epithelium, surrounding mesenchyme derived from splanchnic mesoderm and enteric neuronal components derived from neural crest cells. During gut organogenesis, the mesenchyme differentiates in...
T Narita   K Saitoh   T Kameda   A Kuroiwa   M Mizutani   C Koike   H Iba   S Yasugi   
Development (Cambridge, England) 127(5) 981-8 2000年3月 [査読有り]
Epithelial-mesenchymal interactions are necessary for the normal development of various digestive organs. In chicken proventriculus (glandular stomach), morphogenesis and differentiation of the epithelium depend upon the inductive signals coming f...
T Kameda   C Koike   K Saitoh   A Kuroiwa   H Iba   
Genes to cells : devoted to molecular & cellular mechanisms 4(3) 175-84 1999年3月 [査読有り]
BACKGROUND: The maturation of chondrocytes is essential for endochondral bone formation. The Indian Hedgehog (Ihh) gene is expressed in prehypertropic chondrocytes and has been proposed to regulate chondrocyte maturation. While such secretary fact...