西辻裕紀

研究者氏名	西辻裕紀
	ニシツジヒロノリ
通称等の別名	藤田医科大学
URL
所属	藤田医科大学
部署	ウイルス学
職名	准教授
科研費研究者番号	20573661
J-Global ID	201801009029607414

研究分野

ライフサイエンス / ウイルス学 /

論文

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Modulation of hepatitis B virus infection by epidermal growth factor secreted from liver sinusoidal endothelial cells.

Shin-Wei Chen Misao Himeno Yuta Koui Masaya Sugiyama Hironori Nishitsuji Masashi Mizokami Kunitada Shimotohno Atsushi Miyajima Taketomo Kido

Scientific reports 10(1) 14349-14349 2020年9月

Hepatocytes derived from human iPSCs are useful to study hepatitis B virus (HBV) infection, however infection efficiency is rather poor. In order to improve the efficiency of HBV infection to iPSC-derived hepatocytes, we set a co-culture of hepato...

Orchestration of Intracellular Circuits by G Protein-Coupled Receptor 39 for Hepatitis B Virus Proliferation.

Kaku Goto Hironori Nishitsuji Masaya Sugiyama Nao Nishida Masashi Mizokami Kunitada Shimotohno

International journal of molecular sciences 21(16) 2020年8月

Hepatitis B virus (HBV), a highly persistent pathogen causing hepatocellular carcinoma (HCC), takes full advantage of host machinery, presenting therapeutic targets. Here we aimed to identify novel druggable host cellular factors using the reporte...

Engineering Cellular Biosensors with Customizable Antiviral Responses Targeting Hepatitis B Virus.

Satoko Matsunaga Sundararaj S Jeremiah Kei Miyakawa Daisuke Kurotaki Sayaka Shizukuishi Koichi Watashi Hironori Nishitsuji Hirokazu Kimura Tomohiko Tamura Naoki Yamamoto Kunitada Shimotohno Takaji Wakita Akihide Ryo

iScience 23(3) 100867-100867 2020年3月 [査読有り]

SynNotch receptor technology is a versatile tool that uses the regulatory notch core portion with an extracellular scFv and an intracellular transcription factor that enables to program customized input and output functions in mammalian cells. In ...

Anti-Viral Effects of Interferon-λ3 on Hepatitis B Virus Infection in Cell Culture.

Yamada N Murayama A Shiina M Aly HH Iwamoto M Tsukuda S Watashi K Tanaka T Moriishi K Nishitsuji H Sugiyama M Mizokami M Shimotohno K Muramatsu M Murata K Kato T

Hepatology research : the official journal of the Japan Society of Hepatology 50(3) 283-291 2020年3月 [査読有り]

A new hepatoma cell line exhibiting high susceptibility to hepatitis B virus infection.

Youki Ueda Weilin Gu Hiromichi Dansako Hironori Nishitsuji Shinya Satoh Kunitada Shimotohno Nobuyuki Kato

Biochemical and biophysical research communications 515(1) 156-162 2019年7月 [査読有り]

Hepatitis B virus (HBV) infection, which increases the risk of cirrhosis and hepatocellular carcinoma and requires lifelong treatment, has become a major global health problem. However, host factors essential to the HBV life cycle are still unclea...