Microbiology and immunology 55(3) 160-7 2011年3月 [査読有り]
Flavopiridol is a cyclin-dependent kinase inhibitor and inhibits the growth of various cancer cells. The effect of flavopiridol on lipopolysaccharide (LPS)-induced proinflammatory mediator production was examined in RAW 264.7 macrophage-like cells...
ONO 3403, a new synthetic serine protease inhibitor, is a derivative of camostat mesilate and has a higher protease-inhibitory activity. The effect of ONO 3403 on lipopolysaccharide (LPS)-induced tumor necrosis factor (TNF)-α and nitric oxide (NO)...
The role of retinoblastoma protein-interacting zinc finger 1 (RIZ1) on the cell growth of mouse and human monocytic leukemia cells was examined. RIZ1 expression was induced in response to tumor necrosis factor (TNF)-α. The expression was dependent...
Imtiaz I-E Khuda Naoki Koide Abu S M Noman Jargalsaikhan Dagvadorj Gantsetseg Tumurkhuu Yoshikazu Naiki Takayuki Komatsu Tomoaki Yoshida Takashi Yokochi
Immunology 131(1) 59-66 2010年9月 [査読有り]
Selective Alzheimer disease indicator-1 (seladin-1) is a broadly expressed oxidoreductase and is related to Alzheimer disease, cholesterol metabolism and carcinogenesis. The effect of lipopolysaccharide (LPS) on the expression of seladin-1 was exa...
Abu Shadat Mohammod Noman Naoki Koide Imtiaz Iftakhar-E-Khuda Jargalsaikhan Dagvadorj Gantsetseg Tumurkhuu Yoshikazu Naiki Takayuki Komatsu Tomoaki Yoshida Takashi Yokochi
Immunology letters 131(2) 166-9 2010年7月
The role of retinoblastoma protein-interacting zinc finger 1 (RIZ1) in receptor activator of NF-kappaB ligand (RANKL)-induced osteoclast formation was examined in mouse RAW 264.7 macrophage-like cells. The expression of RIZ1 was significantly augm...
The effect of lipopolysaccharide (LPS) on valproic acid (VPA)-induced cell death was examined by using mouse RAW 264.7 macrophage cells. LPS inhibited the activation of caspase 3 and poly (ADP-ribose) polymerase and prevented VPA-induced apoptosis...
Naoki Koide Yoshikazu Naiki Erdenezaya Odkhuu Bilegtsaikhan Tsolmongyn Takayuki Komatsu Kiyoaki Ito Tomoaki Yoshida Takashi Yokochi
Oncology research 21(1) 59-65 2013年 [査読有り]
A toll-like receptor 4 (TLR-4) ligand, lipopolysaccharide (LPS) not only activates expression and secretion of inflammatory cytokines, but it also often shows toxicity in monocytes. Whether an oncogenic protein, β-catenin, is positively involved i...
The LPS-mediated lethality of NC/Nga mice, having fewer NKT cells, was examined by using d-galactosamine (d-GalN)-sensitization. The NC/Nga mice were not killed by a simultaneous administration of d-GalN and LPS whereas all C57BL/6 (B6) control mi...
Thalidomide is known as an anti-angiogenic, anti-tumor, and anti-proliferative agent, widely used in the treatment of some immunological disorders and cancers. The effect of thalidomide on interferon (IFN)-gamma induced nitric oxide (NO) productio...
お知らせ・マニュアル
医学部