Abu Shadat M Noman Naoki Koide Imtiaz I-E Khuda Jargalsaikhan Dagvadorj Gantsetseg Tumurkhuu Yoshikazu Naiki Takayuki Komatsu Tomoaki Yoshida Takashi Yokochi
FEMS immunology and medical microbiology 56(3) 204-11 2009年8月 [査読有り]
The effect of thalidomide on lipopolysaccharide-induced nitric oxide (NO) production was studied using RAW 264.7 macrophage-like cells. Thalidomide significantly inhibited lipopolysaccharide-induced NO production via reduced expression of an induc...
Jargalsaikhan Dagvadorj Yoshikazu Naiki Gantsetseg Tumurkhuu Abu Shadat Mohammod Noman Imtiaz Iftekar-E-Khuda Naoki Koide Takayuki Komatsu Tomoaki Yoshida Takashi Yokochi
Innate immunity 15(4) 217-24 2009年8月 [査読有り]
The inhibitory effect of interleukin-10 (IL-10), an anti-inflammatory cytokine, on lipopolysaccharide (LPS)-induced IL-6 production was characterized by simultaneous stimulation of RAW 264.7 cells with LPS and IL-10. The presence of IL-10 signific...
Microbiology and immunology 53(5) 295-300 2009年5月 [査読有り]
Nystatin is known to deplete lipid rafts from mammalian cell membranes. Lipid rafts have been reported to be necessary for lipopolysaccharide signaling. In this study, it was unexpectedly found that lipopolysaccharide-induced nitric oxide producti...
The susceptibility of NC/Nga mice to tumor necrosis factor (TNF)-alpha was examined by using sensitization with d-galactosamine (d-GalN). Administration of TNF-alpha and d-GalN killed none of the NC/Nga mice, whereas it killed all of the BALB/c mi...
Abu Shadat M Noman Naoki Koide Ferdaus Hassan Imtiaz I-E-Khuda Jargalsaikhan Dagvadorj Gantsetseg Tumurkhuu Shamima Islam Yoshikazu Naiki Tomoaki Yoshida Takashi Yokochi
Innate immunity 15(1) 33-41 2009年2月 [査読有り]
The effect of thalidomide on lipopolysaccharide (LPS)-induced tumor necrosis factor (TNF)-alpha production was studied by using RAW 264.7 murine macrophage-like cells. Thalidomide significantly inhibited LPS-induced TNF-alpha production. Thalidomi...
The effect of lipopolysaccharide (LPS) on valproic acid (VPA)-induced cell death was examined by using mouse RAW 264.7 macrophage cells. LPS inhibited the activation of caspase 3 and poly (ADP-ribose) polymerase and prevented VPA-induced apoptosis...
Naoki Koide Yoshikazu Naiki Erdenezaya Odkhuu Bilegtsaikhan Tsolmongyn Takayuki Komatsu Kiyoaki Ito Tomoaki Yoshida Takashi Yokochi
Oncology research 21(1) 59-65 2013年 [査読有り]
A toll-like receptor 4 (TLR-4) ligand, lipopolysaccharide (LPS) not only activates expression and secretion of inflammatory cytokines, but it also often shows toxicity in monocytes. Whether an oncogenic protein, β-catenin, is positively involved i...
The LPS-mediated lethality of NC/Nga mice, having fewer NKT cells, was examined by using d-galactosamine (d-GalN)-sensitization. The NC/Nga mice were not killed by a simultaneous administration of d-GalN and LPS whereas all C57BL/6 (B6) control mi...
Thalidomide is known as an anti-angiogenic, anti-tumor, and anti-proliferative agent, widely used in the treatment of some immunological disorders and cancers. The effect of thalidomide on interferon (IFN)-gamma induced nitric oxide (NO) productio...
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