Hirofumi Mizuno Eiji Takayama Ayano Satoh Takeshi Into Masanori Adachi Daisuke Ekuni Koji Yashiro Masako Mizuno-Kamiya Motohiko Nagayama Seitaro Saku Takaaki Tomofuji Yutaka Doi Yukitaka Murakami Nobuo Kondoh Manabu Morita
Experimental and therapeutic medicine 20(3) 2822-2827 2020年9月 [査読有り]
Salivary peroxidase and myeloperoxidase are known to display antibacterial activity against oral microbes, and previous indications have pointed to the possibility that horseradish peroxidase (HRP) adsorbs onto the membrane of the major oral strep...
Akira Kitagawa Yoshiji Ohta Koji Ohashi Koji Yashiro Kenji Fukuzawa
Journal of nutritional science and vitaminology 66(2) 200-206 2020年 [査読有り]
In the present study, we examined the effect of high fructose-induced metabolic syndrome (MetS) on tissue vitamin E and lipid peroxide (LPO) levels in rats. Feeding of a diet containing 60% fructose (HFD) to Wistar rats for 2, 4, and 6 wk caused w...
Akira Hara Satoshi Endo Toshiyuki Matsunaga Midori Soda Koji Yashiro Ossama El-Kabbani
JOURNAL OF BIOCHEMISTRY 162(5) 371-379 2017年11月 [査読有り]
Four human hydroxysteroid dehydrogenases in the aldo-keto reductase (AKR) superfamily, AKR1C1-AKR1C4, are involved in the metabolism of steroids and other carbonyl compounds including drugs, and altered expression of AKRs (1C1, 1C2 and/or 1C3) is ...
Yoshiji Ohta Koji Yashiro Takashi Kobayashi Kazuo Inui Junji Yoshino
FUNDAMENTAL & CLINICAL PHARMACOLOGY 31(3) 319-328 2017年6月 [査読有り]
In the present study, we examined the protective effect of N,N'-dimethylthiourea (DMTU), a scavenger of hydroxyl radical (OH), against water-immersion restraint stress (WIRS)-induced gastric mucosal lesions in rats. When male Wistar rats fasted fo...
Yosihiji Ohta Koji Yashiro Koji Ohashi Yosuke Horikoshi Chiaki Kusumoto Tatsuya Matsura
JOURNAL OF CLINICAL BIOCHEMISTRY AND NUTRITION 60(3) 187-198 2017年5月 [査読有り]
In this study, we examined whether compound 48/80 (C48/80), a mast cell degranulator, causes hepatic oxidative damage in rats. Serum and liver biochemical parameters were determined 0.5, 3 or 6 h after a single treatment with C48/80 (0.75 mg/kg). ...
Guine R(担当:共著, 範囲:Vitamin C deficiency enhances disruption of adrenal non-enzymatic antioxidant defense systems in ODS rats with water-immersion restraint stres)
お知らせ・マニュアル
医学部