JOURNAL OF PHYSIOLOGICAL SCIENCES 67(3) 361-372 2017年5月 [査読有り]
The aim of this study was to clarify the effect of water-immersion restraint stress (WIRS) on tryptophan (Trp) catabolism through the kynurenine (Kyn) pathway in rat tissues. The tissues of rats subjected to 6 h of WIRS (+WIRS) had increased trypt...
ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS 609 69-76 2016年11月 [査読有り]
A human member of the aldo-keto reductase (AKR) superfamily, AKR1B10, is a cytosolic NADPH-dependent reductase toward various carbonyl compounds including reactive aldehydes, and is normally expressed in intestines. The enzyme is overexpressed in ...
JOURNAL OF NUTRITIONAL SCIENCE AND VITAMINOLOGY 61(2) 113-122 2015年4月 [査読有り]
We examined how dietary supplementation of vitamin E protects against liver oxidative damage in rats with water-immersion restraint stress (WIRS). Before WIRS exposure, rats received a normal diet (ND) or vitamin E-supplemented diet (VESD) (500 IU...
CELL BIOCHEMISTRY AND FUNCTION 31(3) 254-262 2013年4月 [査読有り]
We examined whether water-immersion restraint stress (WIRS) disrupts nonenzymatic antioxidant defense systems through ascorbic acid depletion in the adrenal gland of rats. Rats were exposed to WIRS for 0.5, 1.5, 3 or 6h. WIRS increased serum adren...
Journal of Nutritional Science and Vitaminology 59(2) 79-86 2013年 [査読有り]
We examined the effect of vitamin E depletion on liver oxidative damage in rats with water-immersion restraint stress (WIRS). Male Wistar rats were fed a normal diet (N) or vitamin E-depleted diet (VE-D) for 4 wk. N- and VE-D-fed rats were exposed...
Guine R(担当:共著, 範囲:Vitamin C deficiency enhances disruption of adrenal non-enzymatic antioxidant defense systems in ODS rats with water-immersion restraint stres)