Naoki Yahata Yuji Matsumoto Minoru Omi Naoki Yamamoto Ryuji Hata
SCIENTIFIC REPORTS 7(1) 15557 2017年11月 [査読有り]
Induced pluripotent stem cells (iPSCs) are suitable for studying mitochondrial diseases caused by mitochondrial DNA (mtDNA) mutations. Here, we generated iPSCs from a patient with mitochondrial myopathy, encephalopathy, lactic acidosis, and stroke...
JOURNAL OF ALZHEIMERS DISEASE 51(4) 997-1002 2016年 [査読有り]
As a proof of concept that removal of blood amyloid-beta (A beta) can reduce A beta deposition in the brains of patients with Alzheimer's disease, cortices of patients who had undergone hemodialysis (HD), which removes A beta from the blood, were ...
Masahiro Sakanaka Pengxiang Zhu Bo Zhang Tong-Chun Wen Fang Cao Yong-Jie Ma Keiichi Samukawa Noriaki Mitsuda Junya Tanaka Makoto Kuramoto Hidemitsu Uno Ryuji Hatai
JOURNAL OF NEUROTRAUMA 24(6) 1037-1054 2007年6月 [査読有り]
Red ginseng root (Panax Ginseng CA Meyer) has been used clinically by many Asian people for thousands of years without any detrimental effects. One of the major components of Red ginseng root is ginsenoside Rb-1 (gRb1). Previously, we showed that ...
The effects of transient cochlear ischemia on spiral ganglion cells (SGCs) were studied in Mongolian gerbils. Ischemic insult was induced by occluding the bilateral vertebral arteries of gerbils for 15 min. Seven days after ischemia, the percentag...
Shoichiro Takeda Nobuhiro Hakuba Tadashi Yoshida Kensuke Fujita Naohito Hato Ryuji Hata Jun Hyodo Kiyofumi Gyo
NEUROREPORT 19(13) 1325-1328 2008年8月 [査読有り]
The effect of postischemic mild hypothermia on the inner ear has not been clarified. In this study, we investigated whether hypothermia after transient ischemia could prevent cochlear damage and its therapeutic time window. Mongolian gerbils were ...
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医学部