JOURNAL OF CELL BIOLOGY 210(5) 737-751 2015年8月 [査読有り]
Microtubules (MTs) play critical roles in various cellular events, including cell migration. End-binding proteins (EBs) accumulate at the ends of growing MTs and regulate MT end dynamics by recruiting other plus end-tracking proteins (+TIPs). Howe...
MOLECULAR BIOLOGY OF THE CELL 26(4) 751-761 2015年2月 [査読有り]
The organization of the Golgi apparatus is essential for cell polarization and its maintenance. The polarity regulator PAR complex (PAR3, PAR6, and aPKC) plays critical roles in several processes of cell polarization. However, how the PAR complex ...
JOURNAL OF CELL SCIENCE 128(2) 385-396 2015年1月 [査読有り]
The binding of ligand to epidermal growth factor receptor (EGFR) causes the receptor to become activated and stimulates the endocytosis of EGFR. Early endosomes containing activated EGFR migrate along microtubules as they mature into late endosome...
Takashi Watanabe   Shujie Wang   Kozo Kaibuchi   
CELL STRUCTURE AND FUNCTION 40(2) 69-77 2015年 [査読有り]
The actin-cytoskeleton plays a critical role in various biological processes, including cell migration, development, tissue remodeling, and memory formation. Both extracellular and intracellular signals regulate reorganization of the actin-cytoske...