AIMS: Tirzepatide is a novel dual glucagon-like peptide-1 receptor and glucose-dependent insulinotropic polypeptide receptor agonist. We evaluated the pharmacodynamic effects of tirzepatide compared with dulaglutide in patients with type 2 diabete...
Morphological analysis of peripheral nerves in mouse models can be used to characterize the pathophysiology of peripheral nerve disease, but obtaining high-quality electron micrographs can be challenging. Here, we present a protocol to obtain elec...
BACKGROUND: Familial hypocalciuric hypercalcemia (FHH) is a rare autosomal dominant disease, which requires differential diagnosis from relatively common primary hyperparathyroidism (PHPT) in order to avoid unnecessary surgery. CASE PRESENTATION: ...
Journal of diabetes investigation 13(7) 1122-1128 2022年4月 [査読有り][招待有り]
Glucose-dependent insulinotropic polypeptide (GIP) and glucagon-like peptide-1 (GLP-1) are incretins that play an important role in glucose metabolism, by increasing glucose-induced insulin secretion from pancreatic β-cells and help regulate bodyw...
Current biology : CB 32(7) 1485-1496 2022年4月 [査読有り]
Developing animals absorb nutrients either through the placenta or from ingested food; however, the mechanisms by which embryos use external nutrients for individual organ morphogenesis remain to be elucidated. In this study, we assessed nutrient-...
International Diabetes Federation Western Pacific Region Congress2023 15 the Scientific Meeting of the Asian association for the Study of Diabetes 2023年7月21日 [招待有り]