JOURNAL OF ARTIFICIAL ORGANS 18(1) 55-63 2015年3月 [査読有り]
Scaffolds, growth factors, and cells are three essential components in regenerative medicine. Nonwoven filters, which capture cells, provide a scaffold that localizes and concentrates cells near injured tissues. Further, the cells captured on the ...
Elke Guelden   Masaru Ihira   Atsushi Ohashi   Anna Lena Reinbeck   Marina A. Freudenberg   Hubert Kolb   Volker Burkart   
PLOS ONE 8(9) 1-8 2013年9月 [査読有り]
Background/Objective: Toll-like receptors (TLR) mediate the recognition of microbial constituents and stress-induced endogenous ligands by the immune system. They may also be involved in the maintenance or break down of tolerance against autologou...
Journal of Artificial Organs 16(2) 211-217 2013年6月 [査読有り]
Amyloid beta proteins (Aβ) in the brain are the main cause of Alzheimer's disease. Peripheral administration of Aβ-binding substances, which may act as a sink for Aβ from the brain, has been reported to reduce brain Aβ. We previously found C16-cel...
JOURNAL OF NEURAL TRANSMISSION 119(12) 1533-1544 2012年12月 [査読有り]
The pathological changes of Alzheimer's disease include the deposition of amyloid beta protein (A beta) as senile plaques in the brain. We hypothesized that the rapid removal of A beta s from the blood may act as a peripheral A beta drainage sink ...
THERAPEUTIC APHERESIS AND DIALYSIS 15(4) 394-399 2011年8月 [査読有り]
Renal failure is a frequent complication in patients with multiple myeloma. Immunoglobulin free light chains (FLCs) form casts in the distal tubules, resulting in renal obstruction, and are also directly toxic to proximal renal tubules. Removal of...