Nadia P. Castro Natalie D. Fedorova-Abrams Anand S. Merchant Maria Cristina Rangel Tadahiro Nagaoka Hideaki Karasawa Malgorzata Klauzinska Stephen M. Hewitt Kajal Biswas Shyam K. Sharan David S. Salomon
ONCOTARGET 6(14) 11910-11929 2015年5月 [査読有り]
Triple-negative breast cancer (TNBC) presents the poorest prognosis among the breast cancer subtypes and no current standard therapy. Here, we performed an in-depth molecular analysis of a mouse model that establishes spontaneous lung metastasis f...
Tadahiro Nagaoka Ayumu Inutsuka Khadiza Begum Khandakar Musabbir bin Hafiz Masashi Kishi
SCIENTIFIC REPORTS 4 6940 2014年11月 [査読有り]
E-cadherin belongs to the classic cadherin subfamily of calcium-dependent cell adhesion molecules and is crucial for the formation and function of epithelial adherens junctions. In this study, we demonstrate that Vangl2, a vertebrate regulator of ...
Shun Uemura Tadahiro Nagaoka Minesuke Yokoyama Michihiro Igarashi Masashi Kishi
NEUROSCIENCE RESEARCH 80 91-94 2014年3月 [査読有り]
Because genetic manipulation occasionally disrupts the expression of the neighboring genes, the chromosomal locus where the transgene has been integrated should be identified in the use of transgenic organisms. By using a new blend of thermostable...
Tadahiro Nagaoka Riuko Ohashi Ayumu Inutsuka Seiko Sakai Nobuyoshi Fujisawa Minesuke Yokoyama Yina H. Huang Michihiro Igarashi Masashi Kishi
CELL REPORTS 6(5) 916-927 2014年3月 [査読有り]
Although regulators of the Wnt/planar cell polarity (PCP) pathway are widely expressed in vertebrate nervous systems, their roles at synapses are unknown. Here, we show that Vangl2 is a postsynaptic factor crucial for synaptogenesis and that it co...
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