MEDICAL MOLECULAR MORPHOLOGY 49(2) 119-126 2016年6月 [査読有り]
Mesenchymal stem cells (MSCs) represent a promising cell source for stem cell therapy to replace neurons damaged by neurodegenerative diseases. A system designed for in vitro neuronal differentiation of MSCs is an indispensable technique, which pr...
The Dlg1 gene encodes a member of the MAGUK protein family involved in the polarization of epithelial cells. Null mutant mice for the Dlg1 gene (Dlg1(-/-) mice) exhibit respiratory failure and cyanosis, and die soon after birth. However, the cause...
In order to elucidate the function of anti-aromatic acid decarboxylase (AADC)-only-positive cells in the alimentary canal, 5-hydroxy-L-tryptophan (5-HTP) or L-3,4-dihydroxyphenylalanine (L-DOPA) was intraperitoneally injected into the laboratory s...
Background: Loss of adenomatous polyposis coli (APC) gene function results in constitutive activation of the canonical Wnt pathway and represents the main initiating and rate-limiting event in colorectal tumorigenesis. APC is likely to participate...
The adenomatous polyposis coli (APC) tumor suppressor gene is linked to the development of familial adenomatous polyposis and sporadic colorectal tumors. Though APC is highly expressed in the central nervous system (CNS) and directly binds to PSD-...