MEDICAL MOLECULAR MORPHOLOGY 46(1) 14-19 2013年3月 [査読有り]
Lymphocyte enhancer factor 1 (LEF1), a member of the LEF/T-cell-specific factor (TCF) family of the high mobility group domain transcription factors, acts downstream in canonical Wnt signaling. Aberrant transactivation of LEF1 contributes to the t...
MEDICAL MOLECULAR MORPHOLOGY 45(3) 161-167 2012年9月 [査読有り]
Adenomatous polyposis coli (Apc) is a multifunctional protein as well as a tumor suppressor. To determine the functions of the C-terminal domain of Apc, we examined Apc (1638T/1638T) mice that express a truncated Apc lacking the C-terminal domain....
MEDICAL MOLECULAR MORPHOLOGY 44(4) 207-212 2011年12月 [査読有り]
Adenomatous polyposis coli (APC) is a multifunctional protein as well as a tumor suppressor. To determine the functions of the C-terminal domain of Apc, we have investigated Apc (1638T/1638T) mice, which express a truncated Apc that lacks the C-te...
HISTOCHEMISTRY AND CELL BIOLOGY 135(6) 531-538 2011年6月 [査読有り]
Calreticulin (CRT)-1 is a major Ca2+-buffering protein in the lumen of the endoplasmic reticulum. Human and murine CRT-2 was isolated in 2002, but the subcellular localization and function is still unclear. Here, we studied the intracellular local...
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 362(4) 988-994 2007年11月 [査読有り]
ICAT, inhibitor of (beta-catenin and T cell factor, or CtnnbipI, is a negative regulator of the Wnt signaling pathway that interferes with the interaction between beta-catenin and T cell factor. Some ICAT-deficient (ICAT(-/-)) embryos exhibit unil...
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