Patients with severe coronavirus disease 2019 tend to have high levels of proinflammatory cytokines, which eventually lead to cytokine storm and the development of acute respiratory distress syndrome. However, the detailed molecular mechanisms of ...
Herpes simplex virus type 1 (HSV-1) is a ubiquitous pathogen that causes various diseases in humans, ranging from common mucocutaneous lesions to severe life-threatening encephalitis. However, our understanding of the interaction between HSV-1 and...
Yuya Hara   Takahiro Watanabe   Masahiro Yoshida   H M Abdullah Al Masud   Hiromichi Kato   Tomohiro Kondo   Reiji Suzuki   Shutaro Kurose   Md Kamal Uddin   Masataka Arata   Shouhei Miyagi   Yusuke Yanagi   Yoshitaka Sato   Hiroshi Kimura   Takayuki Murata   
Journal of virology e0051822 2022年7月
Protein-protein interactions (PPIs) are crucial for various biological processes. Epstein-Barr virus (EBV) proteins typically form complexes, regulating the replication and persistence of the viral genome in human cells. However, the role of EBV p...
Nasopharyngeal carcinoma (NPC) is caused by infection with Epstein-Barr virus (EBV) and endemic in certain geographic regions. EBV lytic gene, BALF2, closely associates with viral reactivation and BALF2 gene variation, the H-H-H strain, causes NPC...
Cell Communication and Signaling : CCS 20(1) 95-95 2022年6月
BACKGROUND: Viruses must adapt to the environment of their host cells to establish infection and persist. Diverse mammalian cells, including virus-infected cells, release extracellular vesicles such as exosomes containing proteins and miRNAs, and ...