The hypothalamus is comprised of heterogenous cell populations and includes highly complex neural circuits that regulate the autonomic nerve system. Its dysfunction therefore results in severe endocrine disorders. Although recent experiments have ...
Frontiers in Endocrinology 13 941166-941166 2022年7月 [査読有り]
Human stem cell-derived organoid culture enables the in vitro analysis of the cellular function in three-dimensional aggregates mimicking native organs, and also provides a valuable source of specific cell types in the human body. We previously es...
Yu Kodani   Miho Kawata   Hidetaka Suga   Yoko S Kaneko   Akira Nakashima   Toshiki Kameyama   Kanako Saito   Hiroshi Nagasaki   
eNeuro 2022年4月 [査読有り]
Hypothalamic melanin-concentrating hormone (MCH) neurons are important regulators of multiple physiological processes, such as sleep, feeding, and memory. Despite the increasing interest in their neuronal functions, the molecular mechanism underly...
International journal of molecular sciences 23(5) 2022年2月 [査読有り]
Tumor viruses gain control of cellular functions when they infect and transform host cells. Alternative splicing is one of the cellular processes exploited by tumor viruses to benefit viral replication and support oncogenesis. Epstein-Barr virus (...