Kevin J Westbrook   Gayatri Shankar Chilambi   Madison E Stellfox   Hayley R Nordstrom   Yanhong Li   Alina Iovleva   Niyati H Shah   Chelsea E Jones   Ellen G Kline   Kevin M Squires   William R Miller   Truc T Tran   Cesar A Arias   Yohei Doi   Ryan K Shields   Daria Van Tyne   
The Journal of antimicrobial chemotherapy 2024年2月
OBJECTIVES: To investigate the genomic diversity and β-lactam susceptibilities of Enterococcus faecalis collected from patients with infective endocarditis (IE). METHODS: We collected 60 contemporary E. faecalis isolates from definite or probable ...
Hiroshi Yotsuyanagi   Norio Ohmagari   Yohei Doi   Masaya Yamato   Nguyen Hoang Bac   Bong Ki Cha   Takumi Imamura   Takuhiro Sonoyama   Genki Ichihashi   Takao Sanaki   Yuko Tsuge   Takeki Uehara   Hiroshi Mukae   
JAMA network open 7(2) e2354991 2024年2月
IMPORTANCE: Treatment options for COVID-19 are warranted irrespective of the presence of risk factors for severe disease. OBJECTIVE: To assess the efficacy and safety of ensitrelvir in patients with mild to moderate COVID-19. DESIGN, SETTING, AND ...
Makoto Hasegawa   Yasuhiro Osugi   Yoshifumi Moriwaki   Yohei Doi   
Fujita medical journal 10(1) 24-29 2024年2月
OBJECTIVES: Multidrug-resistant (MDR) bacterial infections are highly prevalent among long-term care facility (LTCF) residents, and are thus important targets for antimicrobial stewardship. Diagnoses of urinary tract infections (UTIs), which are a...
Aki Sakurai   Masahiro Suzuki   Kengo Hayashi   Yohei Doi   
Fujita medical journal 10(1) 8-15 2024年2月
OBJECTIVES: Taxonomic assignment based on whole-genome sequencing data facilitates clear demarcation of species within a complex genus. Here, we applied a unique pan-genome phylogenetic method, open reading frame (ORF)-based binarized structure ne...
William Bain   Brian Ahn   Hernán F Peñaloza   Christi L McElheny   Nathanial Tolman   Rick van der Geest   Shekina Gonzalez-Ferrer   Nathalie Chen   Xiaojing An   Ria Hosuru   Mohammadreza Tabary   Erin Papke   Naina Kohli   Nauman Farooq   William Bachman   Tolani F Olonisakin   Zeyu Xiong   Marissa P Griffith   Mara Sullivan   Jonathan Franks   Mustapha M Mustapha   Alina Iovleva   Tomeka Suber   Robert Q Shanks   Viviana P Ferreira   Donna B Stolz   Daria Van Tyne   Yohei Doi   Janet S Lee   
The Journal of infectious diseases 2024年1月
BACKGROUND: Klebsiella pneumoniae carbapenemase-producing K. pneumoniae (KPC-Kp) bloodstream infections are associated with high mortality. We studied clinical bloodstream KPC-Kp isolates to investigate mechanisms of resistance to complement, a ke...