Biochemistry and biophysics reports 27 101086-101086 2021年9月
Human CYP19 spans a region of chromosome 15 of approximately 130 kb and encodes aromatase, an enzyme required for estrogen synthesis. In the human granulosa cell-line KGN, there are seven open chromatin regions within the CYP19 locus. In this stud...
Adipose tissue is a component of the tumor microenvironment and is involved in tumor progression. We have previously shown that adipokine adipsin (CFD) functions as an enhancer of tumor proliferation and cancer stem cell (CSC) properties in breast...
The 'open' and 'compact' regions of chromatin are considered to be regions of active and silent transcription, respectively. However, individual genes produce transcripts at different levels, suggesting that transcription output does not depend on...
Nutrition research (New York, N.Y.) 92 40-48 2021年8月
Some studies have demonstrated that excessive fructose consumption negatively impact brain function. Recently, the Developmental Origins of Health and Disease hypothesis - which suggests that maternal nutritional status during gestation and lactat...
① 抗がん剤(脂肪細胞に高発現するアディプシンを標的とすることでがん幹細胞性を抑制する抗がん剤。日本特許取得)
② ヒト腫瘍異種移植マウス(PDX)。乳がん、大腸がんなど
本研究シーズに関する産学共同研究の問い合わせは藤田医科大学産学連携推進セン
ター(fuji-san@fujita-hu.ac.jp)まで