Researcher Database
Name： Makiko Tsutsumi

Organization / Department (#1)

Organization-1： Fujita Health University

Department(1) 1： Institute for Comprehensive Medical Science

Department(2) 1： Division of Molecular Genetics

Position-1： Assistant Professor

Address-1： 1-98,Toyoake aichi JAPAN

Research History [2006] (#13)

Papers-13： Tsutsumi M., Imai S., Kyono-Hamaguchi Y., Hamaguchi S., Koga A., Hori H. (2006) Color reversion of the albino medaka fish associated with spontaneous somatic excision of the Tol-1 transposable element from the tyrosinase gene. Pigment Cell Res. 19:243-247.

Research History [2007] (#14)

Papers-14： Tsutsumi M., Itoh M. (2007) Novel transcript nort is a downstream target gene of the Notch signaling pathway in zebrafish. Gene Expr. Patterns 7:227-232.

Yokoi H, Shimada A, Carl M, Takashima S, Kobayashi D, Narita T, Jindo T, Kimura T, Kitagawa T, Kage T, Sawada A, Naruse K, Asakawa S, Shimizu N, Mitani H, Shima A, Tsutsumi M, Hori H, Wittbrodt J, Saga Y, Ishikawa Y, Araki K, Takeda H. (2007) Mutant analyses reveal different functions of fgfr1 in medaka and zebrafish despite conserved ligand-receptor relationships. Dev. Biol. 304:326-337.

Research History [2009] (#16)

Papers-16： Kurahashi H, Inagaki H, Kato T, Hosoba E, Kogo H, Ohye T, Tsutsumi M, Bolor H, Tong M, Emanuel BS. (2009) Impaired DNA replication prompts deletions within palindromic sequences, but does not induce translocations in human cells. Hum. Mol. Genet. 18:3397-3406.

Kurahashi H, Bolor H, Kato T, Kogo H, Tsutsumi M, Inagaki H, Ohye T. (2009) Recent advance in our understanding of the molecular nature of chromosomal abnormalities. J. Hum. Genet. 54:253-260.

Bolor H, Mori T, Nishiyama S, Ito Y, Hosoba E, Inagaki H, Kogo H, Ohye T, Tsutsumi M, Kato T, Tong M, Nishizawa H, Pryor-Koishi K, Kitaoka E, Sawada T, Nishiyama Y, Udagawa Y, Kurahashi H. (2009) Mutations of the SYCP3 gene in women with recurrent pregnancy loss. Am. J. Hum. Genet. 84:14-20.

Research History [2010] (#17)

Papers-17： Kurahashi H, Inagaki H, Ohye T, Kogo H, Tsutsumi M, Kato T, Tong M, Emanuel BS. (2010) The constitutional t(11;22): implications for a novel mechanism responsible for gross chromosomal rearrangements. Clin Genet. 78: 299-309.

Tong M, Kato T, Yamada K, Inagaki H, Kogo H, Ohye T, Tsutsumi M, Wang J, Emanuel BS, Kurahashi H. (2010) Polymorphisms of the 22q11.2 breakpoint region influence the frequency of de novo constitutional t(11;22)s in sperm. Hum. Mol. Genet. 19:2630-2637.

Kogo H, Kowa-Sugiyama H, Yamada K, Bolor H, Tsutsumi M, Ohye T, Inagaki H, Taniguchi M, Toda T, Kurahashi H. (2010) Screening of genes involved in chromosome segregation during meiosis I: toward the identification of genes responsible for infertility in humans. J. Hum. Genet. 55:293-299.

Nishizawa H, Kato T, Ota S, Nishiyama S, Pryor-Koishi K, Suzuki M, Tsutsumi M, Inagaki H, Kurahashi H, Udagawa Y. (2010) Genetic variation in the indoleamine 2,3-dioxygenase gene in pre-eclampsia. Am. J. Reprod. Immunol. 64:68-76.

Ohye T, Inagaki H, Kogo H, Tsutsumi M, Kato T, Tong M, Macville MV, Medne L, Zackai EH, Emanuel BS, Kurahashi H. (2010) Paternal origin of the de novo constitutional t(11;22)(q23;q11). Eur. J. Hum. Genet. 18:783-787.

Tsuda S, Kitagawa T, Takashima S, Asakawa S, Shimizu N, Mitani H, Shima A, Tsutsumi M, Hori H, Naruse K, Ishikawa Y, Takeda H. (2010) FAK-mediated extracellular signals are essential for interkinetic nuclear migration and planar divisions in the neuroepithelium. J. Cell Sci. 123:484-496.

Fri Nov 19 17:44:38 JST 2010

Organization / Department (#1)
Organization-1：	Fujita Health University
Department(1) 1：	Institute for Comprehensive Medical Science
Department(2) 1：	Division of Molecular Genetics
Position-1：	Assistant Professor
Address-1：	1-98,Toyoake aichi JAPAN

Research History [2006] (#13)
Papers-13：	Tsutsumi M., Imai S., Kyono-Hamaguchi Y., Hamaguchi S., Koga A., Hori H. (2006) Color reversion of the albino medaka fish associated with spontaneous somatic excision of the Tol-1 transposable element from the tyrosinase gene. Pigment Cell Res. 19:243-247.
Research History [2007] (#14)
Papers-14：	Tsutsumi M., Itoh M. (2007) Novel transcript nort is a downstream target gene of the Notch signaling pathway in zebrafish. Gene Expr. Patterns 7:227-232. Yokoi H, Shimada A, Carl M, Takashima S, Kobayashi D, Narita T, Jindo T, Kimura T, Kitagawa T, Kage T, Sawada A, Naruse K, Asakawa S, Shimizu N, Mitani H, Shima A, Tsutsumi M, Hori H, Wittbrodt J, Saga Y, Ishikawa Y, Araki K, Takeda H. (2007) Mutant analyses reveal different functions of fgfr1 in medaka and zebrafish despite conserved ligand-receptor relationships. Dev. Biol. 304:326-337.
Research History [2009] (#16)
Papers-16：	Kurahashi H, Inagaki H, Kato T, Hosoba E, Kogo H, Ohye T, Tsutsumi M, Bolor H, Tong M, Emanuel BS. (2009) Impaired DNA replication prompts deletions within palindromic sequences, but does not induce translocations in human cells. Hum. Mol. Genet. 18:3397-3406. Kurahashi H, Bolor H, Kato T, Kogo H, Tsutsumi M, Inagaki H, Ohye T. (2009) Recent advance in our understanding of the molecular nature of chromosomal abnormalities. J. Hum. Genet. 54:253-260. Bolor H, Mori T, Nishiyama S, Ito Y, Hosoba E, Inagaki H, Kogo H, Ohye T, Tsutsumi M, Kato T, Tong M, Nishizawa H, Pryor-Koishi K, Kitaoka E, Sawada T, Nishiyama Y, Udagawa Y, Kurahashi H. (2009) Mutations of the SYCP3 gene in women with recurrent pregnancy loss. Am. J. Hum. Genet. 84:14-20.
Research History [2010] (#17)
Papers-17：	Kurahashi H, Inagaki H, Ohye T, Kogo H, Tsutsumi M, Kato T, Tong M, Emanuel BS. (2010) The constitutional t(11;22): implications for a novel mechanism responsible for gross chromosomal rearrangements. Clin Genet. 78: 299-309. Tong M, Kato T, Yamada K, Inagaki H, Kogo H, Ohye T, Tsutsumi M, Wang J, Emanuel BS, Kurahashi H. (2010) Polymorphisms of the 22q11.2 breakpoint region influence the frequency of de novo constitutional t(11;22)s in sperm. Hum. Mol. Genet. 19:2630-2637. Kogo H, Kowa-Sugiyama H, Yamada K, Bolor H, Tsutsumi M, Ohye T, Inagaki H, Taniguchi M, Toda T, Kurahashi H. (2010) Screening of genes involved in chromosome segregation during meiosis I: toward the identification of genes responsible for infertility in humans. J. Hum. Genet. 55:293-299. Nishizawa H, Kato T, Ota S, Nishiyama S, Pryor-Koishi K, Suzuki M, Tsutsumi M, Inagaki H, Kurahashi H, Udagawa Y. (2010) Genetic variation in the indoleamine 2,3-dioxygenase gene in pre-eclampsia. Am. J. Reprod. Immunol. 64:68-76. Ohye T, Inagaki H, Kogo H, Tsutsumi M, Kato T, Tong M, Macville MV, Medne L, Zackai EH, Emanuel BS, Kurahashi H. (2010) Paternal origin of the de novo constitutional t(11;22)(q23;q11). Eur. J. Hum. Genet. 18:783-787. Tsuda S, Kitagawa T, Takashima S, Asakawa S, Shimizu N, Mitani H, Shima A, Tsutsumi M, Hori H, Naruse K, Ishikawa Y, Takeda H. (2010) FAK-mediated extracellular signals are essential for interkinetic nuclear migration and planar divisions in the neuroepithelium. J. Cell Sci. 123:484-496.