総合医科学研究所 難病治療学
Final confirmation time(date):2021/09/11 12:40
Name Kunihiro Tsuchida Affiliation Fujita Health University Section Center for Medical Science Job title Professor Degree M.D.(Kyoto University), Ph.D.(Kyoto University) Research funding number 30281091 J-Global ID 200901025890179259
Profile Our laboratories are involved in development of therapies against intractable diseases including neuromuscular diseases, muscular dystrophies, mood disorders, diabetes/obesity using various cutting-edge technologies.
Research Interests
neuromuscular disorder
,筋ジストロフィー
,健康科学
,ectopic bone formation
,細胞分化
,骨格筋内脂肪蓄積
,脂肪分化
,脂肪蓄積
,exosome
,non-coding RNA
,プロテオミクス
,General Oncology
,ドラッグデリバリー
,ナノテクノロジー
,多能性幹細胞
,臓器再生
,TGF-ベータ
,マイオスタチン
,アクチビン
,フォリスタチン
,アクチビン受容体
Research Areas
Life sciences / Molecular biology /
Life sciences / Medical biochemistry /
Life sciences / Cell biology /
Life sciences / Pathobiochemistry /
Life sciences / Functional biochemistry /
Research History
Jun 2022
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Fujita Health University
Apr 2022
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Fujita Health University Center for Medical Science, Div. Therapy Intrat. Diseases Professor
Oct 2018
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Fujita Health University ICMS Professor
2005
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Fujita Health University ICMS Professor
1998
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2005
The University of Tokushima The Institute for Enzyme Research Associate Professor
Awards
2004
第４５回日本生化学会中国・四国支部会, 学術奨励賞土田邦博
1999
第８１回米国内分泌学会（サンデイエゴ開催）, 研修旅行奨励賞土田邦博
Papers
Hideo Hagihara Hirotaka Shoji Satoko Hattori Giovanni Sala Yoshihiro Takamiya Mika Tanaka Masafumi Ihara Mihiro Shibutani Izuho Hatada Kei Hori Mikio Hoshino Akito Nakao Yasuo Mori Shigeo Okabe Masayuki Matsushita Anja Urbach Yuta Katayama Akinobu Matsumoto Keiichi I Nakayama Shota Katori Takuya Sato Takuji Iwasato Haruko Nakamura Yoshio Goshima Matthieu Raveau Tetsuya Tatsukawa Kazuhiro Yamakawa Noriko Takahashi Haruo Kasai Johji Inazawa Ikuo Nobuhisa Tetsushi Kagawa Tetsuya Taga Mohamed Darwish Hirofumi Nishizono Keizo Takao Kiran Sapkota Kazutoshi Nakazawa Tsuyoshi Takagi Haruki Fujisawa Yoshihisa Sugimura Kyosuke Yamanishi Lakshmi Rajagopal Nanette Deneen Hannah Herbert Y Meltzer Tohru Yamamoto Shuji Wakatsuki Toshiyuki Araki Katsuhiko Tabuchi Tadahiro Numakawa Hiroshi Kunugi Freesia L Huang Atsuko Hayata-Takano Hitoshi Hashimoto Kota Tamada Toru Takumi Takaoki Kasahara Tadafumi Kato Isabella A Graef Gerald R Crabtree Nozomi Asaoka Hikari Hatakama Shuji Kaneko Takao Kohno Mitsuharu Hattori Yoshio Hoshiba Ryuhei Miyake Kisho Obi-Nagata Akiko Hayashi-Takagi Léa J Becker Ipek Yalcin Yoko Hagino Hiroko Kotajima-Murakami Yuki Moriya Kazutaka Ikeda Hyopil Kim Bong-Kiun Kaang Hikari Otabi Yuta Yoshida Atsushi Toyoda Noboru H Komiyama Seth G N Grant Michiru Ida-Eto Masaaki Narita Ken-Ichi Matsumoto Emiko Okuda-Ashitaka Iori Ohmori Tadayuki Shimada Kanato Yamagata Hiroshi Ageta Kunihiro Tsuchida Kaoru Inokuchi Takayuki Sassa Akio Kihara Motoaki Fukasawa Nobuteru Usuda Tayo Katano Teruyuki Tanaka Yoshihiro Yoshihara Michihiro Igarashi Takashi Hayashi Kaori Ishikawa Satoshi Yamamoto Naoya Nishimura Kazuto Nakada Shinji Hirotsune Kiyoshi Egawa Kazuma Higashisaka Yasuo Tsutsumi Shoko Nishihara Noriyuki Sugo Takeshi Yagi Naoto Ueno Tomomi Yamamoto Yoshihiro Kubo Rie Ohashi Nobuyuki Shiina Kimiko Shimizu Sayaka Higo-Yamamoto Katsutaka Oishi Hisashi Mori Tamio Furuse Masaru Tamura Hisashi Shirakawa Daiki X Sato Yukiko U Inoue Takayoshi Inoue Yuriko Komine Tetsuo Yamamori Kenji Sakimura Tsuyoshi Miyakawa
eLife 12 Mar 2024
Increased levels of lactate, an end-product of glycolysis, have been proposed as a potential surrogate marker for metabolic changes during neuronal excitation. These changes in lactate levels can result in decreased brain pH, which has been implic...
Setsuko Komatsu Taiki Kimura Shafiq Ur Rehman Hisateru Yamaguchi Keisuke Hitachi Kunihiro Tsuchida
International journal of molecular sciences 24(18) Sep 2023
Salt stress of soybean is a serious problem because it reduces plant growth and seed yield. To investigate the salt-tolerant mechanism of soybean, a plant-derived smoke (PDS) solution was used. Three-day-old soybeans were subjected to PDS solution...
Atsushi Ohashi Masashi Nakatani Hideo Hori Shigeru Nakai Kunihiro Tsuchida Midori Hasegawa Naotake Tsuboi
Therapeutic Apheresis and Dialysis Aug 2023
Abstract
Shinji Ueno Yusuke Seino Shihomi Hidaka Masashi Nakatani Keisuke Hitachi Naoya Murao Yasuhiro Maeda Haruki Fujisawa Megumi Shibata Takeshi Takayanagi Katsumi Iizuka Daisuke Yabe Yoshihisa Sugimura Kunihiro Tsuchida Yoshitaka Hayashi Atsushi Suzuki
Journal of diabetes investigation 14(9) 1045-1055 Jun 2023
AIMS/INTRODUCTION: Glucagon is secreted from pancreatic α-cells and plays an important role in amino acid metabolism in liver. Various animal models deficient in glucagon action show hyper-amino acidemia and α-cell hyperplasia, indicating that glu...
Tadahiro Nagaoka Tatsuya Katsuno Kyoka Fujimura Kunihiro Tsuchida Masashi Kishi
Scientific reports 13(1) 3905-3905 Mar 2023
Although the core constituents of the Wnt/planar cell polarity (PCP) signaling have been extensively studied, their downstream molecules and protein-protein interactions have not yet been fully elucidated. Here, we show genetic and molecular evide...
Misc.
伊藤 祐太朗 常陸 圭介 土田 邦博
日本生理学雑誌 85(3) 19-19 Aug 2023
上野 慎士 清野 祐介 酒井 志保美 村尾 直哉 中谷 直史 土田 邦博 林 良敬 鈴木 敦詞
糖尿病 66(Suppl.1) S-189 Apr 2023
上野 慎士 清野 祐介 酒井 志保美 中谷 直史 土田 邦博 林 良敬 鈴木 敦詞
日本病態栄養学会誌 26(Suppl.) S-82 Jan 2023
常陸 圭介 清藤 友梨 山口 央輝 中谷 直史 乾 雅史 土田 邦博
日本筋学会学術集会プログラム・抄録集 8回 88-88 Aug 2022
常陸圭介 山口央輝 清藤友梨 中谷直史 乾雅史 小澤龍彦 茅元司 土田邦博
日本分子生物学会年会プログラム・要旨集(Web) 45th 2022
Books and Other Publications
Keisuke Hitachi, Kunihiro Tsuchida(Part:Contributor)
The Chemical Biology of Long Noncoding RNAs. RNA Technologies, vol 11. Springer, Cham. ISBN 9783030447427 Oct 2020
鈴木秀典総編集(Part:Contributor, 作用メカニズムとドーピング 筋肥大阻害（ミオスタチン等）の抑制薬)
中山書店 Feb 2020
Kunihiro Tsuchida, Keisuke Hitachi, Masashi Nakatani, Akiyoshi Uezumi, Hiroshi Ageta(Part:Contributor)
Myostatin: Structure, Role in Muscle Development and Health Implications. Nova Science publishers 2016
Murakami T, Yudasaka M, Iijima S, Tsuchida K(Part:Contributor)
2013
Tsuchida K, Ageta H
Elsevier Mar 2011
Presentations
永岡唯宏 佐々木衿奈 土田邦博
第46回日本分子生物学会年会 6 Dec 2023
大脇有紗 伊藤駿 上田洋司 土田邦博
第44回日本肥満学会・第41回日本肥満症治療学会学術集会 26 Nov 2023
加藤玲奈 常陸圭介 清藤友梨 土田邦博
第9回日本筋学会学術集会・第10回筋ジストロフィー医療研究会合同学術集会 19 Aug 2023
ディニヤアッザラ 木村泰基 山口央輝 常陸圭介 土田邦博 小松節子
日本プロテオーム学会 2023 年大会 Jul 2023
常陸圭介 清藤友梨 山口央輝 中谷直史 乾雅史 土田邦博
第75回動物学会関東支部大会 18 Mar 2023
Teaching Experience
Apr 2020
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Master of Medical Science (Fujita Health University)
Apr 2013
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Human Biology
Apr 2010
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Pathology (Fujita Health University)
Apr 2008
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MD course Molecular Biology (Fujita Health University)
Apr 2007
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Graduation Research (Fujita Health University)
Research Projects
Project Year: Apr 2024 - Mar 2027
Project Year: Apr 2023 - Mar 2026
Project Year: Apr 2018 - Mar 2021
Project Year: 2016 - 2019
Project Year: 2013 - 2015
Education
Apr 1988
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Mar 1992
Kyoto University Graduate School of Medicine Graduate Course
Apr 1982
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Mar 1988
Kyoto University Faculty of Medicine
Committee Memberships
May 2022
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Frontiers in Physiology Associate Editor for Frontiers in Physiology, Striated Muscle Physiology
Jan 2020
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Endocrinology Editorial Board
Feb 2019
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International J. Molecular Sciences, Biochemistry section Editorial Board
Apr 2018
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TCR (Translational Cancer Research) Editorial Board
Other
① 筋萎縮抑制薬開発。
近隣の高等学校から依頼を受け、難病研究の説明や研究室の見学を行なっている。
教育内容・方法の工夫
教育内容・方法の工夫（授業評価等を含む）
件名（英語）
Master of Medical Science
School of Medicine
AnatomyⅠ