研究者氏名	佐野裕美
	サノヒロミ
URL
所属	藤田医科大学
部署	精神・神経病態解明センター
職名	准教授
J-Global ID	200901066461385086

研究キーワード

包括脳ネットワーク ,運動 ,大脳基底核 ,basal-ganglia

研究分野

ライフサイエンス / 分子生物学 /
ライフサイエンス / 医療薬学 /
ライフサイエンス / 生理学 /
ライフサイエンス / 神経科学一般 /

論文

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Identification of Optogenetically Activated Striatal Medium Spiny Neurons by Npas4 Expression

Asim K. Bepari Hiromi Sano Nobuaki Tamamaki Atsushi Nambu Kenji F. Tanaka Hirohide Takebayashi

PLOS ONE 7(12) e52783 2012年12月 [査読有り]

Optogenetics is a powerful neuromodulatory tool with many unique advantages to explore functions of neuronal circuits in physiology and diseases. Yet, interpretation of cellular and behavioral responses following in vivo optogenetic manipulation o...

Expanding the Repertoire of Optogenetically Targeted Cells with an Enhanced Gene Expression System

Kenji F. Tanaka Ko Matsui Takuya Sasaki Hiromi Sano Shouta Sugio Kai Fan Rene Hen Junichi Nakai Yuchio Yanagawa Hidetoshi Hasuwa Masaru Okabe Karl Deisseroth Kazuhiro Ikenaka Akihiro Yamanaka

CELL REPORTS 2(2) 397-406 2012年8月 [査読有り]

Optogenetics has been enthusiastically pursued in recent neuroscience research, and the causal relationship between neural activity and behavior is becoming ever more accessible. Here, we established knockin-mediated enhanced gene expression by im...

Increased social interaction in mice deficient of the striatal medium spiny neuron-specific phosphodiesterase 10A2

Hiromi Sano Yumiko Nagai Tsuyoshi Miyakawa Ryuichi Shigemoto Mineto Ykoi

JOURNAL OF NEUROCHEMISTRY 105(2) 546-556 2008年4月 [査読有り]

Cyclic nucleotide phosphodiesterase 10A (PDE10A) is a member of phosphodiesterase families that degrade cAMP and/or cGMP in distinct intracellular sites. PDE10A has a dual activity on hydrolysis of both cAMP and cGMP, and is prominently expressed ...

Striatal medium spiny neurons terminate in a distinct region in the lateral hypothalamic area and do not directly innervate orexin/hypocretin- or melanin-concentrating hormone-containing neurons

Hiromi Sano Mineto Yokoi

JOURNAL OF NEUROSCIENCE 27(26) 6948-6955 2007年6月 [査読有り]

Neuronal circuits including medium spiny neurons (MSNs) in the nucleus accumbens (NAc) and melanin-concentrating hormone (MCH)-containing neurons in the lateral hypothalamic area (LHA) are hypothesized to play an important role in hedonic feeding....

Transgenic expression of Cre recombinase in mitral/tufted cells of the olfactory bulb

Y Nagai H Sano M Yokoi

GENESIS 43(1) 12-16 2005年9月 [査読有り]

Olfactory information is conveyed from the periphery to the olfactory cortices through mitral and tufted (M/T) cells in the olfactory bulb. A mouse with a specific expression of Cre recombinase in M/T cells is essential for genetic marking of M/T ...

MISC

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Identification and characterization of novel dystonia musculorum mutant mice

H. Takebayashi M. Horie K. K. Mekada H. Sano Y. Kikkawa S. Chiken T. Someya K. Saito M. I. Hossain M. Nameta K. Abe K. Sakimura K. Ono A. Nambu A. Yoshiki

JOURNAL OF NEUROCHEMISTRY 142 229-229 2017年8月

新規自然発生dystonia musculorumマウスの樹立と中枢神経系についての組織学的解析

堀江正男目加田和之目加田和之佐野裕美吉川欣亮知見聡美染谷拓郎斎藤慶介イブラヒムホサインMD 行田正晃阿部訓也崎村建司小野勝彦南部篤吉木淳竹林浩秀

日本解剖学会総会・全国学術集会講演プログラム・抄録集 122nd 196 2017年

Adeno-associated virus-mediated gene transduction of taste cells in vivo

Kashio Makiko Taruno Akiyuki Sun Hongxin Kobayashi Kenta Sano Hiromi Nambu Atsushi Marunaka Yoshinori

CHEMICAL SENSES 41(9) E276-E277 2016年11月 [査読有り]

Pathophysiology and therapy for basal ganglia diseases

H. Sano S. Chiken M. Murata K. Kobayashi A. Nambu

JOURNAL OF NEUROCHEMISTRY 123 37-37 2012年10月

Striatopallidal neurons regulate motor activity through the response pattern in the external segment of globus pallidus and substantia nigra pars reticulata

Hiromi Sano Satomi Chiken Kazuto Kobayashi Atsushi Nambu