JOURNAL OF NEUROSCIENCE 23(37) 11662-11672 2003年12月 [査読有り]
Dopamine D4 receptors (D4R) are localized in the globus pallidus ( GP), but their function remains unknown. In contrast, dopamine D2 receptor activation hyperpolarizes medium spiny neurons projecting from the striatum to the GP and inhibits GABA r...
(1) The basal ganglia circuitry mediates a wide rage of brain functions such as motor control, behavioral planning, and reward prediction. Dopamine (DA) transmission plays an essential role in the regulation of these brain functions. DA action not...
Brain and Development 22(1) S54-S60 2000年9月 [査読有り]
Dopamine is the principal neurotransmitter that mediates a wide range of brain functions, including locomotion, emotion, learning, and neuroendocrine modulation. To clarify the role of dopamine during postnatal development, it is useful to have mu...
K Nishii   N Matsushita   H Sawada   H Sano   Y Noda   T Mamiya   T Nabeshima   Nagatsu, I   T Hata   K Kiuchi   H Yoshizato   K Nakashima   T Nagatsu   K Kobayashi   
JOURNAL OF NEUROSCIENCE RESEARCH 54(4) 450-464 1998年11月 [査読有り]
Mice lacking expression of tyrosine hydroxylase (TH), the first and rate-limiting enzyme of the catecholamine biosynthetic pathway, in dopaminergic neuronal cell types were generated by a transgenic rescue approach to clarify the role of dopamine ...