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研究者リスト >> 大島信子

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大島信子

研究者氏名	大島信子

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所属	藤田医科大学
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職名
学位	博士 (医学)(名古屋大学)
J-Global ID	201501000265589428

研究分野

ライフサイエンス / 分子生物学 /

論文

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Comprehensive Analysis of Antibodies Induced by Vaccination with 4 Kinds of Avian Influenza H5N1 Pre-Pandemic Vaccines

Nobuko Ohshima Yoshitaka Iba Ritsuko Kubota-Koketsu Ayami Yamasaki Keiko Majima Gene Kurosawa Daisuke Hirano Shunji Yoshida Mototaka Sugiura Yoshizo Asano Yoshinobu Okuno Yoshikazu Kurosawa

International Journal of Molecular Sciences 21(19) 7422-7422 2020年10月

Four kinds of avian-derived H5N1 influenza virus, A/Vietnam/1194/2004 (Clade 1), A/Indonesia/5/2005 (Clade 2.1), A/Qinghai/1A/2005 (Clade 2.2), and A/Anhui/1/2005 (Clade 2.3), have been stocked in Japan for use as pre-pandemic vaccines. When a pan...

Isolation of human monoclonal antibodies that bind to two different antigens and are encoded by germline V_H and V_L genes.

Sumitomo-Kondo M Ukai Y Iba Y Ohshima N Miura K Takasaki A Kurosawa Y Kurosawa G

Biochemical and biophysical research communications 503(2) 1141-1147 2018年7月 [査読有り]

Three Types of Broadly Reacting Antibodies against Influenza B Viruses Induced by Vaccination with Seasonal Influenza Viruses.

Hirano D Ohshima N Kubota-Koketsu R Yamasaki A Kurosawa G Okuno Y Yoshida S Kurosawa Y

Journal of immunology research 2018 7251793-7251793 2018年 [査読有り]

Conserved Neutralizing Epitope at Globular Head of Hemagglutinin in H3N2 Influenza Viruses

Yoshitaka Iba Yoshifumi Fujii Nobuko Ohshima Tomomi Sumida Ritsuko Kubota-Koketsu Mariko Ikeda Motoaki Wakiyama Mikako Shirouzu Jun Okada Yoshinobu Okuno Yoshikazu Kurosawa Shigeyuki Yokoyama

JOURNAL OF VIROLOGY 88(13) 7130-7144 2014年7月 [査読有り]

Neutralizing antibodies that target the hemagglutinin of influenza virus either inhibit binding of hemagglutinin to cellular receptors or prevent the low-pH-induced conformational change in hemagglutinin required for membrane fusion. In general, t...

Receptor mimicry by antibody F045-092 facilitates universal binding to the H3 subtype of influenza virus

Peter S. Lee Nobuko Ohshima Robyn L. Stanfield Wenli Yu Yoshitaka Iba Yoshinobu Okuno Yoshikazu Kurosawa Ian A. Wilson

NATURE COMMUNICATIONS 5 3614 2014年4月 [査読有り]

Influenza viruses present a significant health challenge each year, as in the H3N2 epidemic of 2012-2013. Here we describe an antibody, F045-092, that possesses broadly neutralizing activity against the entire H3 subtype and accommodates the natur...