研究者氏名	武藤久哲
	ﾑﾄｳﾋｻﾉﾘ
URL
所属	藤田医科大学
部署	医学部　消化器内科学
職名	講師
J-Global ID	202301017613610349

研究分野

ライフサイエンス / 消化器内科学 /

論文

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Clinical Outcomes With Lenvatinib in Patients Previously Treated With Atezolizumab/Bevacizumab for Advanced Hepatocellular Carcinoma.

Hisanori Muto Teiji Kuzuya Naoto Kawabe Eizaburo Ohno Kohei Funasaka Mitsuo Nagasaka Yoshihito Nakagawa Ryoji Miyahara Tomoyuki Shibata Senju Hashimoto Yoshiaki Katano Yoshiki Hirooka

Anticancer research 43(10) 4673-4682 2023年10月

BACKGROUND/AIM: The combination of atezolizumab plus bevacizumab (Atz/Bev) has become widely used as a first-line therapy for advanced hepatocellular carcinoma (HCC). However, for post-Atz/Bev therapy, evidence on the outcomes of molecular targete...

Proteomic Analysis Reveals Changes in Tight Junctions in the Small Intestinal Epithelium of Mice Fed a High-Fat Diet.

Hisanori Muto Takashi Honda Taku Tanaka Shinya Yokoyama Kenta Yamamoto Takanori Ito Norihiro Imai Yoji Ishizu Keiko Maeda Tetsuya Ishikawa Shungo Adachi Chikara Sato Noriko M Tsuji Masatoshi Ishigami Mitsuhiro Fujishiro Hiroki Kawashima

Nutrients 15(6) 2023年3月

The impact of a high-fat diet (HFD) on intestinal permeability has been well established. When bacteria and their metabolites from the intestinal tract flow into the portal vein, inflammation in the liver is triggered. However, the exact mechanism...

Conditioned medium from stem cells derived from human exfoliated deciduous teeth ameliorates NASH via the Gut-Liver axis.

Hisanori Muto Takanori Ito Taku Tanaka Shinya Yokoyama Kenta Yamamoto Norihiro Imai Yoji Ishizu Keiko Maeda Takashi Honda Tetsuya Ishikawa Asuka Kato Taichi Ohshiro Fumiya Kano Akihito Yamamoto Kiyoshi Sakai Hideharu Hibi Masatoshi Ishigami Mitsuhiro Fujishiro

Scientific reports 11(1) 18778-18778 2021年9月

Non-alcoholic steatohepatitis (NASH) occurrence has been increasing and is becoming a major cause of liver cirrhosis and liver cancer. However, effective treatments for NASH are still lacking. We examined the benefits of serum-free conditioned med...

Transient deterioration of albumin-bilirubin scores in early post-dose period of molecular targeted therapies in advanced hepatocellular carcinoma with 50% or higher liver occupation: A STROBE-compliant retrospective observational study.

Hisanori Muto Teiji Kuzuya Takanori Ito Yoji Ishizu Takashi Honda Tetsuya Ishikawa Masatoshi Ishigami Mitsuhiro Fujishiro

Medicine 100(31) e26820 2021年8月

Real-world clinical cases of molecularly targeted agent (MTA) administration to patients with advanced hepatocellular carcinoma (HCC) with ≥50% liver occupation have been reported, but treatment outcomes have rarely been described. We have encount...

肝占拠率50%以上の肝細胞癌に対する分子標的治療早期のALBIスコアの変化に注目して

武藤久哲葛谷貞二藤城光弘

日本消化器病学会雑誌 118(臨増総会) A356-A356 2021年3月