Evgeniia Borisova   Ken Nishimura   Yuri An   Miho Takami   Jingyue Li   Dan Song   Mami Matsuo-Takasaki   Dorian Luijkx   Shiho Aizawa   Akihiro Kuno   Eiji Sugihara   Taka-Aki Sato   Fumiaki Yumoto   Tohru Terada   Koji Hisatake   Yohei Hayashi   
iScience 25(1) 103525-103525 2022年1月
Non-genetically modified somatic cells can only be inefficiently and stochastically reprogrammed to pluripotency by exogenous expression of reprogramming factors. Low competence of natural reprogramming factors may prevent the majority of cells to...
Structural analysis of small supernumerary marker chromosomes (sSMCs) has revealed that many have complex structures. Structural analysis of sSMCs by whole genome sequencing using short-read sequencers is challenging however because most present w...
Reprogramming of murine female somatic cells to induced pluripotent stem cells (iPSCs) is accompanied by X chromosome reactivation (XCR), by which the inactive X chromosome (Xi) in female somatic cells becomes reactivated. However, how Xi initiate...
Upper urinary tract urothelial carcinoma (UTUC) is one of the common urothelial cancers. Its molecular pathogenesis, however, is poorly understood, with no useful biomarkers available for accurate diagnosis and molecular classification. Through an...
Journal of orthopaedic research : official publication of the Orthopaedic Research Society 2021年3月 [査読有り]
Osteosarcoma is the most common high-grade malignancy of bone, and novel therapeutic options are urgently required. Previously, we developed mouse osteosarcoma AXT cells that can proliferate both under adherent and non-adherent conditions. Based o...