International journal of hematology 118(1) 107-118 2023年7月
Chemotherapy with cytarabine, vincristine (VCR), and prednisolone has achieved low mortality rates in pediatric patients with Langerhans cell histiocytosis (LCH). However, relapse rates remain high, making event-free survival (EFS) rates unsatisfa...
Makito Tanaka Hiroki Miura Soichiro Ishimaru Gen Furukawa Yoshiki Kawamura Kei Kozawa Seiji Yamada Fumitaka Ito Kazuko Kudo Tetsushi Yoshikawa
Pediatric reports 15(2) 333-340 2023年5月
Central nervous system (CNS) involvement in anaplastic large cell lymphoma (ALCL) at diagnosis is rare and leads to poor prognosis with the use of the standard ALCL99 protocol alone. CNS-directed intensive chemotherapy, such as an increased dose o...
Eczema herpeticum (EH) is a disseminated cutaneous infection with herpes simplex virus (HSV) that develops in patients with atopic dermatitis. The kinetics and clinical significance of HSV viremia in EH are poorly understood. Herein, we report HSV...
[Rinsho ketsueki] The Japanese journal of clinical hematology 63(5) 373-382 2022年
Langerhans cell histiocytosis (LCH) is characterized by immature dendritic cell proliferation, which is currently classified as an inflammatory myeloid neoplasm. Clinical features and outcomes vary from spontaneously regressing isolated bone disea...
Myeloid leukemia in Down syndrome (ML-DS) is associated with good response to chemotherapy and favorable prognosis. Because little research has been focused on refractory/relapsed (R/R) cases, we conducted a retrospective analysis for R/R ML-DS. A...
PEDIATRIC BLOOD & CANCER 59(1) 110-114 2012年7月 [査読有り]
Background Hemophagocytic lymphohistiocytosis (HLH) is associated with hypercytokinemia in children. Although HLH can be also observed after hematopoietic stem cell transplantation (HSCT), the incidence and clinical features of HLH after HSCT rema...
PEDIATRIC BLOOD & CANCER 58(5) 780-784 2012年5月 [査読有り]
Background Idiopathic pneumonia syndrome (IPS) is a severe complication that can occur after hematopoietic stem cell transplantation (HSCT) and is often associated with a fatal outcome despite intensive supportive care. Procedure. To assess the in...
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