研究者氏名	黒澤仁
	クロサワジン
URL	http://kaken.nii.ac.jp/d/r/10410739.ja.html
所属	藤田医科大学
部署	その他部局等
職名
学位	理学博士(名古屋大学)
J-Global ID	201401018482788607

研究キーワード

腫瘍学 ,抗体

研究分野

ライフサイエンス / 腫瘍診断、治療学 /

論文

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In Vitro Tumor Cell-Binding Assay to Select High-Binding Antibody and Predict Therapy Response for Personalized 64Cu-Intraperitoneal Radioimmunotherapy against Peritoneal Dissemination of Pancreatic Cancer: A Feasibility Study.

Fukiko Hihara Hiroki Matsumoto Mitsuyoshi Yoshimoto Takashi Masuko Yuichi Endo Chika Igarashi Tomoko Tachibana Mitsuhiro Shinada Ming-Rong Zhang Gene Kurosawa Aya Sugyo Atsushi B Tsuji Tatsuya Higashi Hiroaki Kurihara Makoto Ueno Yukie Yoshii

International journal of molecular sciences 23(10) 2022年5月 [査読有り]

Peritoneal dissemination of pancreatic cancer has a poor prognosis. We have reported that intraperitoneal radioimmunotherapy using a 64Cu-labeled antibody (64Cu-ipRIT) is a promising adjuvant therapy option to prevent this complication. To achieve...

Hepatoprotective Effects of Aureobasidium pullulans Derived β 1,3-1,6 Glucans in a Murine Model of Non-alcoholic Steatohepatitis.

Nobunao Ikewaki Gary A Levy Gene Kurosawa Masaru Iwasaki Vidyasagar D Dedeepiya Suryaprakash Vaddi Rajappa Senthilkumar Senthilkumar Preethy Samuel J K Abraham

Journal of clinical and experimental hepatology 12(6) 1428-1437 2022年 [査読有り]

BACKGROUND: Non-alcoholic fatty liver disease (NAFLD) and non-alcoholic steatohepatitis (NASH) are highly prevalent conditions characterized by inflammation and fibrosis of the liver, which can progress to cirrhosis and hepatocellular carcinoma if...

β‑glucan vaccine adjuvant approach for cancer treatment through immune enhancement (B‑VACCIEN) in specific immunocompromised populations (Review).

Nobunao Ikewaki Vidyasagar Devaprasad Dedeepiya Kadalraja Raghavan Kosagi-Sharaf Rao Suryaprakash Vaddi Hiroshi Osawa Tomohiko Kisaka Gene Kurosawa Subramaniam Srinivasan Seydunganallu Ramasamy Balaganesa Kumar Rajappa Senthilkumar Masaru Iwasaki Senthilkumar Preethy Samuel J K Abraham

Oncology reports 47(1) 2022年1月 [査読有り]

The incidence of cancer, which is the second leading cause of mortality globally, continues to increase, although continued efforts are being made to identify effective treatments with fewer side‑effects. Previous studies have reported that chroni...

β-glucans: wide-spectrum immune-balancing food-supplement-based enteric (β-WIFE) vaccine adjuvant approach to COVID-19.

Nobunao Ikewaki Masaru Iwasaki Gene Kurosawa Kosagi-Sharaf Rao Johant Lakey-Beitia Senthilkumar Preethy Samuel Jk Abraham

Human vaccines & immunotherapeutics 17(8) 1-6 2021年3月 [査読有り]

Conventional vaccines to combat COVID-19 through different approaches are at various stages of development. The complexity of COVID-19 such as the potential mutations of the virus leading to antigenic drift and the uncertainty on the duration of t...

Comprehensive Analysis of Antibodies Induced by Vaccination with 4 Kinds of Avian Influenza H5N1 Pre-Pandemic Vaccines.

Nobuko Ohshima Yoshitaka Iba Ritsuko Kubota-Koketsu Ayami Yamasaki Keiko Majima Gene Kurosawa Daisuke Hirano Shunji Yoshida Mototaka Sugiura Yoshizo Asano Yoshinobu Okuno Yoshikazu Kurosawa

International journal of molecular sciences 21(19) 2020年10月 [査読有り]

Four kinds of avian-derived H5N1 influenza virus, A/Vietnam/1194/2004 (Clade 1), A/Indonesia/5/2005 (Clade 2.1), A/Qinghai/1A/2005 (Clade 2.2), and A/Anhui/1/2005 (Clade 2.3), have been stocked in Japan for use as pre-pandemic vaccines. When a pan...