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研究者リスト >> 大島信子

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大島信子

研究者氏名	大島信子

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所属	藤田医科大学
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職名
学位	博士 (医学)(名古屋大学)
J-Global ID	201501000265589428

研究分野

ライフサイエンス / 分子生物学 /

論文

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Identification of a human homologue of the DREF transcription factor with a potential role in regulation of the histone H1 gene

N Ohshima M Takahashi F Hirose

JOURNAL OF BIOLOGICAL CHEMISTRY 278(25) 22928-22938 2003年6月 [査読有り]

A human homologue (hDREF/KIAA0785) of Drosophila DREF, a transcriptional regulatory factor required for expression of genes involved in DNA replication and cell proliferation, was identified by BLAST search. Amino acid sequences corresponding to t...

Transcription control of a gene for Drosophila transcription factor, DREF by DRE and cis-elements conserved between Drosophila melanogaster and virilis

E Kwon H Seto F Hirose N Ohshima Y Takahashi Y Nishida M Yamaguchi

GENE 309(2) 101-116 2003年5月 [査読有り]

A DNA replication-related element (DRE)-binding factor (DREF) has been revealed to be an important transcription factor for activating promoters of cell proliferation and differentiation related genes. The amino acid sequences of DREF are conserve...

Drosophila Mi-2 negatively regulates dDREF by inhibiting its DNA-binding activity

F Hirose N Ohshima EJ Kwon H Yoshida M Yamaguchi

MOLECULAR AND CELLULAR BIOLOGY 22(14) 5182-5193 2002年7月 [査読有り]

Drosophila melanogaster DNA replication-related element (DRE) factor (dDREF) is a transcriptional regulatory factor required for the expression of genes carrying the 5'-TATCGATA DRE. dDREF has been reported to bind to a sequence in the chromatin b...

Ectopic expression of DREF induces DNA synthesis, apoptosis, and unusual morphogenesis in the Drosophila eye imaginal disc: Possible interaction with polycomb and trithorax group proteins

F Hirose N Ohshima M Shiraki YH Inoue O Taguchi Y Nishi A Matsukage M Yamaguchi

MOLECULAR AND CELLULAR BIOLOGY 21(21) 7231-7242 2001年11月 [査読有り]

The promoters of Drosophila genes encoding DNA replication-related proteins contain transcription regulatory element DRE (5'-TATCGATA) in addition to E2F recognition sites. A specific DRE-binding factor, DREF, positively regulates DRE-containing g...

Isolation of cDNAs encoding cellular drug-binding proteins using a novel expression cloning procedure: Drug-western

H Tanaka N Ohshima H Hidaka

MOLECULAR PHARMACOLOGY 55(2) 356-363 1999年2月 [査読有り]

A rapid and convenient new method for isolating the genes encoding cellular drug-binding proteins is described. This method, drug-western, is based on the use of the drug conjugated with a marker molecule as a probe for the screening of a cDNA lib...