N Ohshima   M Takahashi   F Hirose   
JOURNAL OF BIOLOGICAL CHEMISTRY 278(25) 22928-22938 2003年6月 [査読有り]
A human homologue (hDREF/KIAA0785) of Drosophila DREF, a transcriptional regulatory factor required for expression of genes involved in DNA replication and cell proliferation, was identified by BLAST search. Amino acid sequences corresponding to t...
A DNA replication-related element (DRE)-binding factor (DREF) has been revealed to be an important transcription factor for activating promoters of cell proliferation and differentiation related genes. The amino acid sequences of DREF are conserve...
F Hirose   N Ohshima   EJ Kwon   H Yoshida   M Yamaguchi   
MOLECULAR AND CELLULAR BIOLOGY 22(14) 5182-5193 2002年7月 [査読有り]
Drosophila melanogaster DNA replication-related element (DRE) factor (dDREF) is a transcriptional regulatory factor required for the expression of genes carrying the 5'-TATCGATA DRE. dDREF has been reported to bind to a sequence in the chromatin b...
MOLECULAR AND CELLULAR BIOLOGY 21(21) 7231-7242 2001年11月 [査読有り]
The promoters of Drosophila genes encoding DNA replication-related proteins contain transcription regulatory element DRE (5'-TATCGATA) in addition to E2F recognition sites. A specific DRE-binding factor, DREF, positively regulates DRE-containing g...
A rapid and convenient new method for isolating the genes encoding cellular drug-binding proteins is described. This method, drug-western, is based on the use of the drug conjugated with a marker molecule as a probe for the screening of a cDNA lib...